2',4,4',6'-TETRAMETHOXYCHALCONE

Base Information

• Chemical Name: 2',4,4',6'-TETRAMETHOXYCHALCONE
• CAS No.: 94103-36-3
• Molecular Formula: C19H20O5
• Molecular Weight: 328.365
• Mol file: 94103-36-3.mol

Synonyms:(E)-3-(4-methoxyphenyl)-1-(2,4,6-trimethoxyphenyl)prop-2-en-1-one;4.2'.4'.6'-tetramethoxy-trans(?)-chalcone;(E)-3-(4-Methoxy-phenyl)-1-(2,4,6-trimethoxy-phenyl)-propenone;4.2'.4'.6'-Tetramethoxy-trans(?)-chalkon;2',4',6',4-tetramethoxychalcone;(2E)-3-(4-methoxyphenyl)-1-(2,4,6-trimethoxyphenyl)propenone;4,2',4',6'-tetramethoxychalcone;

Chemical Property of 2',4,4',6'-TETRAMETHOXYCHALCONE

Chemical Property:

• Melting Point: 119 °C
• PSA: 53.99000
• LogP: 3.61710

Purity/Quality:

99% ^*data from raw suppliers

(E)-1-(2,4,6-Trimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: N
• Statements: 50/53
• Safety Statements: 60-61

MSDS Files:

Useful:

Technology Process of 2',4,4',6'-TETRAMETHOXYCHALCONE

There total 11 articles about 2',4,4',6'-TETRAMETHOXYCHALCONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

4-methoxy-benzaldehyde (123-11-5) + 1-(2,4,6-trimethoxyphenyl)ethanone (832-58-6) → (2E)-1-(2,4,6-trimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one (94103-36-3)

Guidance literature:

With potassium hydroxide; In ethanol; at 20 ℃; for 6h;

DOI:10.1002/jccs.200100033

Reference yield: 89.0%

1-(2,4,6-trimethoxyphenyl)ethanone (832-58-6) + 1-(4-methoxyphenyl)ethanone (100-06-1) → (2E)-1-(2,4,6-trimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one (94103-36-3)

Guidance literature:

With sodium hydroxide; In methanol; at 20 ℃;

DOI:10.1016/j.bmc.2017.01.049

Reference yield: 47.0%

dimethyl sulfate (77-78-1) + naringenin (480-41-1) → (2E)-1-(2,4,6-trimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one (94103-36-3)

Guidance literature:

With potassium carbonate; In acetone; at 40 - 45 ℃;

DOI:10.1155/2021/4817900

upstream raw materials:

methyl p-toluene sulfonate

dimethyl sulfate

helichrysetin

methyl iodide

Downstream raw materials:

3,4',5,7-tetramethoxyflavone

5-hydroxy-3,4',7-trimethoxyflavone

kaempferol 5,7,4'-trimethyl ether

4',7,-di-O-methylkaempferol