Potassium methoxy-methyltrifluoroborate

Base Information

• Chemical Name: Potassium methoxy-methyltrifluoroborate
• CAS No.: 910251-11-5
• Molecular Formula: C2H5BF3O.K
• Molecular Weight: 151.966
• Hs Code.: 2931900090
• Mol file: 910251-11-5.mol

Synonyms:K[CH3OCH2BF3];potassium trifluoro(methoxymethyl)boranuide;potassium methoxymethyl trifluoroborate;potassium trifluoro(methoxymethyl)borate;potassium ion trifluoro(methoxymethyl)boranuide;

Chemical Property of Potassium methoxy-methyltrifluoroborate

Chemical Property:

• Melting Point: 153°C(lit.)
• PSA: 9.23000
• LogP: 1.43770
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

98% ^*data from raw suppliers

Potassium (Methoxymethyl)trifluoroborate ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-37

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Potassium methoxy-methyltrifluoroborate

There total 4 articles about Potassium methoxy-methyltrifluoroborate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

potassium bromomethyl trifluoroborate + methanol (67-56-1) → potassium trifluoro(methoxymethyl)boranuide (910251-11-5)

Guidance literature:

methanol; With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃; for 0.75h; Inert atmosphere;

potassium bromomethyl trifluoroborate; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/jacs.6b03399

Reference yield: 91.0%

potassium bromomethyl trifluoroborate + sodium methylate (124-41-4) → potassium trifluoro(methoxymethyl)boranuide (910251-11-5)

Guidance literature:

potassium bromomethyl trifluoroborate; sodium methylate; In tetrahydrofuran; at 0 - 20 ℃; for 14h; Inert atmosphere;

With potassium hydrogen bifluoride; In tetrahydrofuran; water; at 20 ℃; for 0.5h; pH=6;

DOI:10.1021/ol800532p

Reference yield: 54.0%

methanol (67-56-1) + potassium chloromethyltrifluoroborate → potassium trifluoro(methoxymethyl)boranuide (910251-11-5)

Guidance literature:

methanol; With potassium hydride; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

potassium chloromethyltrifluoroborate; In tetrahydrofuran; at 0 - 50 ℃; Inert atmosphere;

DOI:10.1021/ol201469r

upstream raw materials:

tributyl(methoxymethyl)stannane

sodium methylate

methanol

Downstream raw materials:

1-methoxymethyl-4-nitrobenzene

1-methoxy-2-methoxymethylbenzene

1-(4-(methoxymethyl)phenyl)ethanone

p-methoxymethylbenzoic acid methyl ester

Refernces

• 1、 Molander, Gary A.,Beaumard, Floriane. "Cross-coupling of mesylated phenol derivatives with potassium alkoxymethyltrifluoroborates". supporting information; experimental part. p. 3948 - 3951. Retrieved 2011/09/16.
• 2、 -. "HYDROXYMETHYLBORON COMPOUNDS". Page/Page column 20. . Retrieved 2010/11/29.