Methyl 4-(MethoxyMethyl)benzoate

Base Information

• Chemical Name: Methyl 4-(MethoxyMethyl)benzoate
• CAS No.: 1719-82-0
• Molecular Formula: C10H12O3
• Molecular Weight: 180.203
• Mol file: 1719-82-0.mol

Synonyms:methyl 4-(methoxymethyl)benzoate;

Chemical Property of Methyl 4-(MethoxyMethyl)benzoate

Chemical Property:

• PSA: 35.53000
• LogP: 1.61960

Purity/Quality:

99% ^*data from raw suppliers

Methyl4-(Methoxymethyl)benzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methyl 4-(MethoxyMethyl)benzoate

There total 15 articles about Methyl 4-(MethoxyMethyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methyl 4-(dimethoxymethyl)benzoate (42228-16-0) → p-methoxymethylbenzoic acid methyl ester (1719-82-0)

Guidance literature:

With 1,1,3,3-Tetramethyldisiloxane; copper(II) bis(trifluoromethanesulfonate); In dichloromethane; at 20 ℃;

DOI:10.1039/c1gc15636e

Reference yield: 88.0%

methyl 4-formylbenzoate (1571-08-0) + trimethyl orthoformate (149-73-5) → p-methoxymethylbenzoic acid methyl ester (1719-82-0)

Guidance literature:

With C₁₈H₄BCl₃F₈; hydrogen; In tetrahydrofuran; at 80 ℃; for 48h; under 15001.5 Torr;

DOI:10.1002/anie.201700231

Reference yield: 87.0%

methanol (67-56-1) + 4-(Methoxymethyl)benzoic acid (67003-50-3) → p-methoxymethylbenzoic acid methyl ester (1719-82-0)

Guidance literature:

With thionyl chloride; at -30 - 20 ℃; for 4h;

DOI:10.1002/ejoc.200390090

upstream raw materials:

deuteromethanol

Methyl 4-(bromomethyl)benzoate

dibenzylphosphine oxide

Dimethyl phosphite

Downstream raw materials:

4-methyloxymethylhydroxymethylhydroxymethylcyclohexane

methyl 4-formylbenzoate

4-(methoxymethyl)benzaldehyde

4-chloromethylbenzaldehyde