Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1)

Base Information

• Chemical Name: Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1)
• CAS No.: 1014645-87-4
• Molecular Formula: C11H14ClNO2
• Molecular Weight: 227.691
• Hs Code.: 2922499990
• Mol file: 1014645-87-4.mol

Synonyms:Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1);Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1)/4-(1-Aminocyclopropyl)benzoic acid methyl ester hydrochloride;Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride

Chemical Property of Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1)

Chemical Property:

• PSA: 52.32000
• LogP: 2.92330
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

4-(1-Amino-cyclopropyl)-benzoicacidmethylesterhydrochloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1)

There total 8 articles about Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-(1-aminocyclopropyl)-benzoic acid methyl ester (1006037-03-1) → methyl 4-(1-aminocyclopropyl)benzoate hydrochloride (1014645-87-4)

Guidance literature:

With hydrogenchloride; In diethyl ether; ethyl acetate;

Reference yield: 95.6%

methanol (67-56-1) + 4-(1-aminocyclopropyl)benzoic acid hydrochloride (1014645-83-0) → methyl 4-(1-aminocyclopropyl)benzoate hydrochloride (1014645-87-4)

Guidance literature:

With thionyl chloride; Reflux;

Reference yield:

methyl 4-(1-((tert-butoxycarbonyl)amino)cyclopropyl)benzoate (1338243-88-1) → methyl 4-(1-aminocyclopropyl)benzoate hydrochloride (1014645-87-4)

Guidance literature:

With hydrogenchloride; In ethyl acetate; at 20 ℃;

upstream raw materials:

methanol

4-(1-aminocyclopropyl)benzoic acid hydrochloride

4-(1-aminocyclopropyl)-benzoic acid methyl ester

4-(1-aminocyclopropyl)benzoic acid

Downstream raw materials:

methyl 4-{1-[({2,5-dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]cyclopropyl}benzoate

C₂₃H₁₈Cl₂F₃N₃O₄

ER-888363-00

methyl 4-(1-(2-(3-((3-fluorophenyl)amino)azetidin-1-yl)-5-(trifluoromethyl)nicotinamido)cyclopropyl)benzoate