(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol

Base Information

Chemical Name:(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
CAS No.:133775-25-4
Molecular Formula:C₁₂H₁₃F₂N₃O₂
Molecular Weight:269.251
Hs Code.:
European Community (EC) Number:818-289-4
UNII:1F8K4N408B
Mol file:133775-25-4.mol

Synonyms:133775-25-4;(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol;(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol;Efinaconazole metabolite H2;1F8K4N408B;(2R,3R)-2-(2,4-DIFLUOROPHENYL)-1-(1,2,4-TRIAZOL-1-YL)BUTANE-2,3-DIOL;2,3-Butanediol, 2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-, (2R,3R)-;132507-94-9;((2R,3R)-2-(2,4-Difluorophenyl)-1-(1,2,4-triazol-1-YL)butane-2,3-diol);135270-11-0;UNII-1F8K4N408B;SCHEMBL2912761;LSCNANBNVFQJDJ-PRHODGIISA-N;BCP14909;CS-M3126;MFCD28902278;AKOS027324641;DS-11530;L10001;A854596;(2R, 3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol;(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butandiol

Suppliers and Price of (2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol
50mg
$ 50.00

Crysdot
(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol 95+%
5g
$ 285.00

Crysdot
(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol 95+%
10g
$ 475.00

ChemScene
2,3-Butanediol,2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-,(2R,3R)- 99.68%
5g
$ 54.00

ChemScene
2,3-Butanediol,2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-,(2R,3R)- 99.68%
1g
$ 50.00

ChemScene
2,3-Butanediol,2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-,(2R,3R)- 99.68%
10g
$ 95.00

Chemenu
(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol 95+%
1000g
$ 5040.00

Biosynth Carbosynth
(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3
5 g
$ 280.00

Biosynth Carbosynth
(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3
2 g
$ 156.00

Biosynth Carbosynth
(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3
10 g
$ 470.00

Total 106 raw suppliers

Chemical Property of (2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol

Chemical Property:

PSA：71.17000
LogP:0.82490
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:Chloroform (Slightly), DMSO (Slightly)
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:269.09758299
Heavy Atom Count:19
Complexity:311

Purity/Quality:

99%, ^*data from raw suppliers

(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C(CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)O
Isomeric SMILES:C[C@H]([C@](CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)O
Uses (2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-Butanediol is a useful reagent for preparing phenylisoxazole derivatives as CYP3A4 inhibitors, which also exhibit antifungal activity.

Technology Process of (2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol

There total 61 articles about (2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%