4-Bromo-2-methyl-3-nitropyridine

Base Information

Chemical Name:4-Bromo-2-methyl-3-nitropyridine
CAS No.:23056-49-7
Molecular Formula:C6H5BrN2O2
Molecular Weight:217.022
Hs Code.:2933399090
DSSTox Substance ID:DTXSID10702245
Wikidata:Q82634097
Mol file:23056-49-7.mol

Synonyms:4-Bromo-2-methyl-3-nitropyridine;23056-49-7;4-BROMO-2-METHYL-3-NITRO-PYRIDINE;MFCD11215573;Pyridine, 4-bromo-2-methyl-3-nitro-;SCHEMBL2596737;DTXSID10702245;HLWBVEFKUQEPPM-UHFFFAOYSA-N;AS-78225;SY269115;CS-0146012;FT-0757213;F18275

Suppliers and Price of 4-Bromo-2-methyl-3-nitropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Bromo-2-methyl-3-nitropyridine 95+%
1g
$ 698.00

Chemenu
4-bromo-2-methyl-3-nitropyridine 95%
1g
$ 660.00

Atlantic Research Chemicals
4-Bromo-2-methyl-3-nitropyridine 95%
1gm:
$ 519.58

Alichem
4-Bromo-2-methyl-3-nitropyridine
250mg
$ 1048.60

Alichem
4-Bromo-2-methyl-3-nitropyridine
1g
$ 2952.90

AK Scientific
4-Bromo-2-methyl-3-nitropyridine
5g
$ 2085.00

AK Scientific
4-Bromo-2-methyl-3-nitropyridine
250mg
$ 316.00

Total 9 raw suppliers

Chemical Property of 4-Bromo-2-methyl-3-nitropyridine

Chemical Property:

Boiling Point:240.8±35.0 °C(Predicted)
PKA:2.03±0.10(Predicted)
PSA：58.71000
Density:1.709±0.06 g/cm3(Predicted)
LogP:2.58390
Storage Temp.:Inert atmosphere,Store in freezer, under -20°C
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:215.95344
Heavy Atom Count:11
Complexity:159

Purity/Quality:

97% ^*data from raw suppliers

4-Bromo-2-methyl-3-nitropyridine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC=CC(=C1[N+](=O)[O-])Br

Technology Process of 4-Bromo-2-methyl-3-nitropyridine

There total 5 articles about 4-Bromo-2-methyl-3-nitropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.7%

: 18614-66-9
2-methyl-3-nitro-4-pyridinol

: 23056-49-7
4-bromo-2-methyl-3-nitropyridine

Guidance literature:: With phosphorus(V) oxybromide; at 140 ℃; for 3h; pressure vessel;

Reference yield:

: 18614-65-8
2-methyl-4-pyridinol nitrate

: 23056-49-7
4-bromo-2-methyl-3-nitropyridine

: 4-bromo-2-methyl-5-nitropyridine

Guidance literature:: 2-methyl-4-pyridinol nitrate; With sulfuric acid; nitric acid; at 0 - 130 ℃;

With phosphorus(V) oxybromide; In toluene; for 10h; Overall yield = 92 %; Overall yield = 1.46 g; Reflux; Inert atmosphere;
DOI:10.1021/acs.joc.7b00323

Reference yield:

: 18437-58-6
3-methyl-4-pyridinamine

: 23056-49-7
4-bromo-2-methyl-3-nitropyridine

Guidance literature:: Multi-step reaction with 3 steps

1: nitric acid; sodium nitrite / water / -17 - 0 °C

2: nitric acid; sulfuric acid / 25 - 130 °C

3: phosphorus(V) oxybromide / 3 h / 140 °C / pressure vessel

With sulfuric acid; nitric acid; sodium nitrite; phosphorus(V) oxybromide; In water;