1,2,2-Trimethyl-1,3-cyclopentanedicarboxylic acid dimethyl ester

Base Information

• Chemical Name: 1,2,2-Trimethyl-1,3-cyclopentanedicarboxylic acid dimethyl ester
• CAS No.: 7282-27-1
• Molecular Formula: C₁₂H₂₀O₄
• Molecular Weight: 228.288
• Hs Code.: 2933698090
• Mol file: 7282-27-1.mol

Synonyms:1,2,2-Trimethyl-1,3-cyclopentanedicarboxylic acid dimethyl ester

Chemical Property of 1,2,2-Trimethyl-1,3-cyclopentanedicarboxylic acid dimethyl ester

Chemical Property:

• Vapor Pressure: 0.0092mmHg at 25°C
• Boiling Point: 265.4°C at 760 mmHg
• Flash Point: 119.8°C
• PSA: 52.60000
• Density: 1.033g/cm³
• LogP: 1.77490

Purity/Quality:

99%, ^*data from raw suppliers

Dimethyl1,2,2-trimethylcyclopentane-1,3-dicarboxylate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2,2-Trimethyl-1,3-cyclopentanedicarboxylic acid dimethyl ester

There total 22 articles about 1,2,2-Trimethyl-1,3-cyclopentanedicarboxylic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) → α-Methylhydrogen-dl-isocamphersaeure (306935-15-9) + 1,2,2-trimethyl-cyclopentane-1,3-dicarboxylic acid dimethyl ester (7282-27-1,16089-19-3,29606-96-0)

Guidance literature:

With sulfuric acid; -dimethyl ester;

DOI:10.1021/ja02257a022

Reference yield:

(1S,3R)-(-)-camphoric acid (560-09-8) + methyl iodide (74-88-4) → (1S,3R)-dimethyl 1,2,2-trimethylcyclopentane-1,3-dicarboxylate (7282-27-1,15797-21-4,16089-19-3,20221-16-3,26252-17-5,26371-73-3,29606-96-0,29606-97-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 13 ℃; for 3h;

Reference yield:

sodium ethanolate (141-52-6) → 1,2,2-trimethyl-cyclopentane-1,3-dicarboxylic acid dimethyl ester (7282-27-1,16089-19-3,29606-96-0)

Guidance literature:

With methyl iodide; at 100 ℃; -dimethyl ester; im geschlossenen Rohr;

upstream raw materials:

methanol

2,2-dimethyl-cyclopentane-1,1,3-tricarboxylic acid

dimethyl sulfate

camphoric acid

Downstream raw materials:

(+/-)-3-methyl hydrogen 2,2,3-trimethyl-cis-1,3-cyclopentanedicarboxylate

(+/-)-1.2.2-trimethyl-3c-benzoyl-cyclopentane-carboxylic acid-(1r)

monomethyl ester of (+)-camphoric acid

(1S,3S)-1,2,2-Trimethyl-cyclopentane-1,3-dicarboxylic acid 1-methyl ester