Diamidafos

Base Information

• Chemical Name: Diamidafos
• CAS No.: 1754-58-1
• Molecular Formula: C8H13 N2 O2 P
• Molecular Weight: 200.177
• European Community (EC) Number: 217-144-7
• UNII: 8NX8P1GOF9
• DSSTox Substance ID: DTXSID6041846
• Nikkaji Number: J7.768B
• Wikidata: Q27155775
• Mol file: 1754-58-1.mol

Synonyms:diamidafos;diamidfos;phenyl N,N'-dimethylphosphorodiamidate

Chemical Property of Diamidafos

Chemical Property:

• Melting Point: 103.5°C
• Boiling Point: 273.8±23.0 °C(Predicted)
• PKA: 3.43±0.70(Predicted)
• Flash Point: 119.4oC
• PSA: 60.17000
• Density: 1.165±0.06 g/cm3(Predicted)
• LogP: 2.39410
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 200.07146466
• Heavy Atom Count: 13
• Complexity: 185

Purity/Quality:

99.9% ^*data from raw suppliers

Diamidafos ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Pesticides -> Organophosphate Insecticides
• Canonical SMILES: CNP(=O)(NC)OC1=CC=CC=C1
• Uses: Diamidafos is a useful building block and a pesticide whose residues are sometimes found in fruits and vegetables.

Technology Process of Diamidafos

There total 1 articles about Diamidafos which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

O-phenyl phosphorodichloridate (770-12-7) + methylamine (74-89-5) → Bis(methylamido)phosphorsaeure-phenylester (1754-58-1)

Guidance literature:

In tetrahydrofuran; for 4h; Ambient temperature;

Reference yield: 91.0%

oxalyl dichloride (79-37-8) + Bis(methylamido)phosphorsaeure-phenylester (1754-58-1) → 1,3-dimethyl-2-phenoxy-1,3,2-diazaphospholidine-2,4,5-trione (74518-35-7)

Guidance literature:

In various solvent(s); for 3h; Heating;

Reference yield: 73.0%

2-ethylmalonyl dichloride (55552-69-7) + Bis(methylamido)phosphorsaeure-phenylester (1754-58-1) → 2-Phenyloxy-1,3-dimethyl-5-ethyl-4,6-dioxo-hexahydro-1,3,2-diazphosphorin-2-oxid (82960-98-3)

Guidance literature:

With potassium carbonate; In chloroform; 1.) reflux, 2 h, 2.) room temp., overnight;

DOI:10.1002/ardp.19823150704

upstream raw materials:

O-phenyl phosphorodichloridate

methylamine

Downstream raw materials:

Phosphorsaeure-phenylester-di-(N-chlor-methylamid)

C₁₄H₂₉N₂O₂PSi₂

2-Phenyloxy-1,3-dimethyl-5,5-diethyl-4,6-dioxo-hexahydro-1,3,2-diazphosphorin-2-oxid

2-Phenyloxy-1,3-dimethyl-4,6-dioxo-hexahydro-1,3,2-diazphosphorin-2-oxid

Refernces

• 1、 Mollin, Jiri,Laznicka, Jiri,Kasparek, Frantisek. "ALKALINE SOLVOLYSIS OF DIAMIDOPHOSPHATES". . p. 232 - 242. Retrieved 2007/10/02.
• 2、 Mulliez, M.. "SYNTHESE DE TRIOXO-2,4,5-DIAZA-1,3-PHOSPHOLIDINES-2-TRISUBSTITUTEES ET REACTIONS AVEC LES ALCOOLS ET LES AMINES". . p. 27 - 36. Retrieved 2007/10/02.