3-Iodo-7-methyl-1H-pyrrolo[3,2-B]pyridine

Base Information

Chemical Name:3-Iodo-7-methyl-1H-pyrrolo[3,2-B]pyridine
CAS No.:1190312-40-3
Molecular Formula:C8H7IN2
Molecular Weight:258.05905
Hs Code.:
DSSTox Substance ID:DTXSID10696610
Wikidata:Q82626290
Mol file:1190312-40-3.mol

Synonyms:3-IODO-7-METHYL-1H-PYRROLO[3,2-B]PYRIDINE;1190312-40-3;3-IODO-7-METHYL-4-AZAINDOLE;SCHEMBL1984578;DTXSID10696610;IDSWTOXKAOXKTI-UHFFFAOYSA-N;FT-0715152

Suppliers and Price of 3-Iodo-7-methyl-1H-pyrrolo[3,2-B]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Iodo-7-methyl-1H-pyrrolo[3,2-b]pyridine 95+%
1g
$ 680.00

Chemenu
3-Iodo-7-methyl-1H-pyrrolo[3,2-b]pyridine 95%
1g
$ 636.00

Chemcia Scientific
3-Iodo-7-methyl-1H-pyrrolo[3,2-b]pyridine 95%
1 G
$ 495.00

Alichem
3-Iodo-7-methyl-1H-pyrrolo[3,2-b]pyridine
1g
$ 723.16

Total 3 raw suppliers

Chemical Property of 3-Iodo-7-methyl-1H-pyrrolo[3,2-B]pyridine

Chemical Property:

PSA：28.68000
LogP:2.47590
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:257.96540
Heavy Atom Count:11
Complexity:151

Purity/Quality:

98% ^*data from raw suppliers

3-Iodo-7-methyl-1H-pyrrolo[3,2-b]pyridine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C2C(=NC=C1)C(=CN2)I

Technology Process of 3-Iodo-7-methyl-1H-pyrrolo[3,2-B]pyridine

There total 6 articles about 3-Iodo-7-methyl-1H-pyrrolo[3,2-B]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 357263-42-4
7-methyl-1H-pyrrolo[3,2-b]pyridine

: 1190312-40-3
3-iodo-7-methyl-1H-pyrrolo[3,2-b]pyridine

Guidance literature:: With N-iodo-succinimide; In tetrahydrofuran; for 2h;

Reference yield:

: 272-49-1
1H-pyrrolo[3,2-b]pyridine

: 1190312-40-3
3-iodo-7-methyl-1H-pyrrolo[3,2-b]pyridine

Guidance literature:: Multi-step reaction with 4 steps

1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 16 h / 0 - 20 °C / Inert atmosphere

2.1: trichlorophosphate / 2 h / 120 °C / Inert atmosphere

3.1: caesium carbonate / 1,4-dioxane / 0.17 h / 20 °C / Inert atmosphere

3.2: 16 h / 120 °C / Inert atmosphere

4.1: N-iodo-succinimide / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere

With N-iodo-succinimide; caesium carbonate; 3-chloro-benzenecarboperoxoic acid; trichlorophosphate; In tetrahydrofuran; 1,4-dioxane; dichloromethane;
DOI:10.1021/jm500571f

Reference yield:

: 1116136-36-7
1H-pyrrolo[3,2-b]pyridine 4-oxide

: 1190312-40-3
3-iodo-7-methyl-1H-pyrrolo[3,2-b]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1.1: trichlorophosphate / 2 h / 120 °C / Inert atmosphere

2.1: caesium carbonate / 1,4-dioxane / 0.17 h / 20 °C / Inert atmosphere

2.2: 16 h / 120 °C / Inert atmosphere

3.1: N-iodo-succinimide / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere

With N-iodo-succinimide; caesium carbonate; trichlorophosphate; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1021/jm500571f