DiMethyl 2,5-dibroMoisophthalate

Base Information

• Chemical Name: DiMethyl 2,5-dibroMoisophthalate
• CAS No.: 1337958-87-8
• Molecular Formula: C10H8Br2O4
• Molecular Weight: 351.97612
• Hs Code.: 2917399090
• Mol file: 1337958-87-8.mol

Synonyms:DiMethyl 2,5-dibroMoisophthalate

Chemical Property of DiMethyl 2,5-dibroMoisophthalate

Chemical Property:

• PSA: 52.60000
• LogP: 2.78480
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

Dimethyl2,5-dibromoisophthalate >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DiMethyl 2,5-dibroMoisophthalate

There total 4 articles about DiMethyl 2,5-dibroMoisophthalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

methanol (67-56-1) + 2,5-dibromoisophthalic acid (379711-35-0) → dimethyl 2,5-dibromoisophthalate (1337958-87-8)

Guidance literature:

With sulfuric acid; for 18h; Reflux;

DOI:10.1021/jo202623u

Reference yield: 50.4%

dimethyl Isophthalate (1459-93-4) → dimethyl 2,5-dibromoisophthalate (1337958-87-8) + 2,5-dibromoisophthalic acid (379711-35-0) + 4,5-dibromoisophthalic acid (379711-34-9) + dimethyl 4,5-dibromoisophthalate (244768-63-6) + isophthalic acid (121-91-5) + dimethyl 5-bromoisophthalate (51760-21-5) + 5-bromoisophthalic acid (23351-91-9)

Guidance literature:

With sulfuric acid; sulfur trioxide; bromine; at 120 ℃; for 7h;

Reference yield:

2,5-dibromo-1,3-dimethylbenzene (100189-84-2) → dimethyl 2,5-dibromoisophthalate (1337958-87-8)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium permanganate / water; tert-butyl alcohol / 19 h / Reflux

2: sulfuric acid / 18 h / Reflux

With potassium permanganate; sulfuric acid; In water; tert-butyl alcohol;

DOI:10.1021/jo202623u

upstream raw materials:

dimethyl Isophthalate

methanol

2,5-dibromoisophthalic acid

4-bromo-2,6-dimethylphenylamine

Downstream raw materials:

5-bromo-2-((2-methoxyphenyl)(phenyl)amino)isophthalic acid

Refernces

• 1、 -. "Process for the preparation of bromoisophthalic acid compounds". Page 4. . Retrieved 2010/02/05.