2-Chloro-3-(2-thenoyl)pyridine

Base Information

• Chemical Name: 2-Chloro-3-(2-thenoyl)pyridine
• CAS No.: 125035-34-9
• Molecular Formula: C10H6ClNOS
• Molecular Weight: 223.683
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID10568823
• Wikidata: Q82455201
• Mol file: 125035-34-9.mol

Synonyms:2-CHLORO-3-(2-THENOYL)PYRIDINE;125035-34-9;(2-chloropyridin-3-yl)-thiophen-2-ylmethanone;MFCD02260467;2-chloro-3-(2-thiophenecarbonyl)pyridine;SCHEMBL5210328;DTXSID10568823;BOABLMHZQMXLBD-UHFFFAOYSA-N;AKOS016018730;2-chloro-3-(2-thienylcarbonyl)pyridine;(2-chloropyridin-3-yl)(2-thienyl)methanone;Methanone, (2-chloro-3-pyridinyl)-2-thienyl-;(2-Chloropyridin-3-yl)(thiophen-2-yl)methanone

Chemical Property of 2-Chloro-3-(2-thenoyl)pyridine

Chemical Property:

• Vapor Pressure: 9.19E-06mmHg at 25°C
• Boiling Point: 373.1°C at 760 mmHg
• Flash Point: 179.4°C
• PSA: 58.20000
• Density: 1.379g/cm³
• LogP: 3.02750
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 222.9858627
• Heavy Atom Count: 14
• Complexity: 224

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-3-(2-thenoyl)pyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(N=C1)Cl)C(=O)C2=CC=CS2

Technology Process of 2-Chloro-3-(2-thenoyl)pyridine

There total 5 articles about 2-Chloro-3-(2-thenoyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

(2-chloropyridin-3-yl)(thiophen-2-yl)methanol → 2-chloro-3-(2-thiophenecarbonyl)pyridine (125035-34-9)

Guidance literature:

With manganese(IV) oxide;

DOI:10.1055/s-0030-1260152

Reference yield:

2-Chloronicotinoyl chloride (49609-84-9) → 2-chloro-3-(2-thiophenecarbonyl)pyridine (125035-34-9)

Guidance literature:

With carbon disulfide; aluminium trichloride; In thiophene; ethyl acetate;

Reference yield:

2-chloronicotinic acid (2942-59-8) + tin(IV) chloride (7646-78-8) → 2-chloro-3-(2-thiophenecarbonyl)pyridine (125035-34-9)

Guidance literature:

With thionyl chloride; In thiophene; 1,1-dichloroethane;

upstream raw materials:

2-Chloronicotinoyl chloride

2-chloronicotinic acid

tin(IV) chloride

2-chloropyridine

Downstream raw materials:

(2-methoxypyridin-3-yl)(thiophen-2-yl)methanone

2-(6-dimethylaminohexyloxy)-3-(2-thenoyl)pyridine