2-Allyloxyethanol

Base Information

• Chemical Name: 2-Allyloxyethanol
• CAS No.: 111-45-5
• Molecular Formula: C5H10O2
• Molecular Weight: 102.133
• Hs Code.: 29094990
• European Community (EC) Number: 203-871-7,608-071-5,936-588-9
• NSC Number: 32614
• UNII: 852300B9QS
• DSSTox Substance ID: DTXSID0059401
• Nikkaji Number: J38.384H
• Wikidata: Q27896790
• Mol file: 111-45-5.mol

Synonyms:2-allyloxyethanol;2-allyloxyethyl alcohol;Lioxasol

Chemical Property of 2-Allyloxyethanol

Chemical Property:

• Appearance/Colour: colorless and transparent liquid
• Vapor Pressure: 0.929mmHg at 25°C
• Refractive Index: n20/D 1.436(lit.)
• Boiling Point: 158.5 °C at 760 mmHg
• PKA: 14.50±0.10(Predicted)
• Flash Point: 55 °C
• PSA: 29.46000
• Density: 0.928 g/cm³
• LogP: 0.18130
• Storage Temp.: 2-8°C
• Solubility.: Completely miscible in water
• Water Solubility.: 454g/L at 25℃
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 102.068079557
• Heavy Atom Count: 7
• Complexity: 43.3

Purity/Quality:

99% ^*data from raw suppliers

2-Allyloxyethanol ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 38-41-36/37/38
• Safety Statements: 26-39-45-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CCOCCO

Technology Process of 2-Allyloxyethanol

There total 15 articles about 2-Allyloxyethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

ethylene glycol (107-21-1) + allyl bromide (106-95-6) → ethylene glycol monoallyl ether (111-45-5,27274-31-3)

Guidance literature:

With sodium hydride; In dimethyl sulfoxide; for 3h;

Reference yield: 78.0%

2-(prop-2-ynyloxy)ethanol (3973-18-0) → ethylene glycol monoallyl ether (111-45-5,27274-31-3)

Guidance literature:

2-(prop-2-ynyloxy)ethanol; With lithium aluminium tetrahydride; In 1,4-dioxane; at -5 ℃; for 6h; Reflux;

With water; sodium hydroxide; In 1,4-dioxane; at 0 ℃;

DOI:10.1134/S1070363213010295

Reference yield: 78.0%

ethylene glycol (107-21-1) + 3-chloroprop-1-ene (107-05-1) → ethylene glycol monoallyl ether (111-45-5,27274-31-3)

Guidance literature:

With potassium hydroxide;

DOI:10.1007/BF02220020

upstream raw materials:

oxirane

allyl alcohol

ethylene glycol

2-vinyl-1,3-dioxolane

Downstream raw materials:

maleic acid-(2-allyloxy-ethyl ester)-methyl ester

allyloxyethyl 2-methacrylic acid

acetic acid 2-allyloxyethyl ester

2-(allyloxy)acetaldehyde

Refernces

• 1、 Riemschneider,Koetzsch. "-". . p. 787,788,790. Retrieved 1959.
• 2、 Gharibyan,Petrosyan,Makaryan,Hovhannisyan,Chobanyan, Zh. A.. "Reduction of ethylene glycol monopropargyl ether by lithium aluminum hydride". . . Retrieved 2013.
• 3、 Ali-Adib, Ziad,Bomben, Andrea,Davis, Frank,Hodge, Philip,Tundo, Pietro,Valli, Ludovico. "Examples of amphitropic polymers: Monolayer film, Langmuir-Blodgett film and liquid-crystalline properties of some polymeric amphiphiles containing cholestanol moieties and those of some closely related non-polymeric amphiphiles". . p. 15 - 22. Retrieved 1996.
• 4、 -. "Non-natural amino acid and application thereof Recombinant protein and recombinant protein conjugate comprising same". Paragraph 0094; 0098; 0099-0100. . Retrieved 2021/10/27.