4-Pyridinecarboxamide, N-methyl-

Base Information

Chemical Name:4-Pyridinecarboxamide, N-methyl-
CAS No.:6843-37-4
Molecular Formula:C7H8 N2 O
Molecular Weight:136.153
Hs Code.:2933399090
NSC Number:87279
UNII:QEV857ZE95
DSSTox Substance ID:DTXSID70218554
Nikkaji Number:J600.114I
Wikidata:Q72492216
Mol file:6843-37-4.mol

Synonyms:1-methylisonicotinamide

Suppliers and Price of 4-Pyridinecarboxamide, N-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Methylisonicotinamide
1g
$ 1010.00

American Custom Chemicals Corporation
N-METHYL-4-PYRIDINECARBOXAMIDE 95.00%
5MG
$ 499.51

Total 6 raw suppliers

Chemical Property of 4-Pyridinecarboxamide, N-methyl-

Chemical Property:

Vapor Pressure:5.3E-05mmHg at 25°C
Melting Point:115 °C(Solv: benzene (71-43-2))
Boiling Point:347.7°C at 760 mmHg
PKA:13.65±0.46(Predicted)
Flash Point:164.1°C
PSA：41.99000
Density:1.106g/cm³
LogP:0.83210
XLogP3:0
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:136.063662883
Heavy Atom Count:10
Complexity:119

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

N-Methylisonicotinamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC(=O)C1=CC=NC=C1
Uses N-Methylisonicotinamide is a methyl derivative of Isonicotinamide (I821700); a compound that strongly induced apoptosis in human acute myelomonocytic leukemia cells, HL-60. N-Methylisonicotinamide is also used as a reagent in the synthesis of the alkaloid eupolauramine.

Technology Process of 4-Pyridinecarboxamide, N-methyl-

There total 2 articles about 4-Pyridinecarboxamide, N-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 2.0%

: 694-59-7
pyridine N-oxide

: 123-39-7
N-Methylformamide

: 110-86-1
pyridine

: 6144-78-1
N-methylpyridine-2-carboxamide

: 6843-37-4
N-methylisonicotinamide

Guidance literature:: for 120h; Heating;

Reference yield:

: 2459-09-8
4-pyridinecarboxylic acid, methyl ester

: 57-14-7
N,N-Dimethylhydrazine

: 55-22-1
pyridine-4-carboxylic acid

: 6843-37-4
N-methylisonicotinamide

: 74-89-5
methylamine

Guidance literature:: at 130 ℃;
DOI:10.1039/jr9550004315

Reference yield: 99.0%

: 6843-37-4
N-methylisonicotinamide

: 1903-75-9
N-methyl-4-piperidinecarboxamide hydrochloride

Guidance literature:: With 1,1,2-trichloroethane; palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 8h; under 760.051 Torr;
DOI:10.1016/j.tet.2009.08.011