2-(4-(2-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-2-ylimino)thiazolidin-4-one

Base Information

• Chemical Name: 2-(4-(2-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-2-ylimino)thiazolidin-4-one
• CAS No.: 1620666-96-7
• Molecular Formula: C₁₉H₁₁Cl₃N₄OS
• Molecular Weight: 449.748
• Mol file: 1620666-96-7.mol

Synonyms:2-(4-(2-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-2-ylimino)thiazolidin-4-one

Chemical Property of 2-(4-(2-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-2-ylimino)thiazolidin-4-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-(2-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-2-ylimino)thiazolidin-4-one

There total 2 articles about 2-(4-(2-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-2-ylimino)thiazolidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(2-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-2-amine (1354922-08-9) + potassium thioacyanate (333-20-0) + acetone (67-64-1) → 2-(4-(2-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-2-ylimino)thiazolidin-4-one (1620666-96-7)

Guidance literature:

for 4h; Reflux;

DOI:10.1016/j.ejmech.2014.06.033

Reference yield:

1-(2,4-dichlorophenyl)ethan-1-one (2234-16-4) → 2-(4-(2-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-2-ylimino)thiazolidin-4-one (1620666-96-7)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydroxide / ethanol; water

2: sodium hydroxide / water; N,N-dimethyl-formamide / Reflux

3: 4 h / Reflux

With sodium hydroxide; In ethanol; water; N,N-dimethyl-formamide;

DOI:10.1016/j.ejmech.2014.06.033

Reference yield:

2-(4-(2-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-2-ylimino)thiazolidin-4-one (1620666-96-7) + benzaldehyde (100-52-7) → 5-benzylidene-2-(4-(2-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-2-ylimino) thiazolidin-4-one (1620666-97-8)

Guidance literature:

With sodium acetate; In acetic acid; Microwave irradiation;

DOI:10.1016/j.ejmech.2014.06.033

upstream raw materials:

4-(2-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-2-amine

potassium thioacyanate

acetone

1-(2,4-dichlorophenyl)ethan-1-one

Downstream raw materials:

4-(2-chlorophenyl)-N-(4-(2-chlorophenyl)-3a,4-dihydro-1H-pyrido[1,2-a]thiazolo[5,4-e]pyrimid in-2(10aH)-ylidene)-6-(2,4-dichlorophenyl)pyrimidin-2-amine

5-benzylidene-2-(4-(2-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-2-ylimino) thiazolidin-4-one

2-(4-(2-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-2-ylimino)-5-(4-methoxybenzylidene)thiazolidin-4-one

2-(4-(2-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-2-ylimino)-5-(furan-2ylmethylene)thiazolidin-4-one