o-(Ethoxymethyl)anisole

Base Information

• Chemical Name: o-(Ethoxymethyl)anisole
• CAS No.: 64988-06-3
• Molecular Formula: C10H14 O2
• Molecular Weight: 166.22
• Hs Code.: 2909309090
• European Community (EC) Number: 265-301-3
• UNII: B4GR6Q7FDH
• DSSTox Substance ID: DTXSID5052333
• Nikkaji Number: J286.622F
• Wikidata: Q81985002
• Mol file: 64988-06-3.mol

Synonyms:o-(Ethoxymethyl)anisole;64988-06-3;Ethyl o-methoxybenzyl ether;Ethyl 2-methoxybenzyl ether;1-(ethoxymethyl)-2-methoxybenzene;o-Methoxybenzyl ethyl ether;2-Methoxybenzyl ethyl ether;Ether, ethyl o-methoxybenzyl;1-Ethoxymethyl-2-methoxybenzene;Benzene, 1-(ethoxymethyl)-2-methoxy-;EINECS 265-301-3;o-Methoxybenzyl alcohol, ethyl ether;B4GR6Q7FDH;BRN 2087623;0-06-00-00893 (Beilstein Handbook Reference);UNII-B4GR6Q7FDH;o - (ethoxymethyl)anisole;Ethyl-2-methoxybenzyl ether;SCHEMBL585111;DTXSID5052333;ETHER, ETHYL 2-METHOXYBENZYL;LS-30328

Chemical Property of o-(Ethoxymethyl)anisole

Chemical Property:

• Vapor Pressure: 0.246mmHg at 25°C
• Refractive Index: 1.4778 (estimate)
• Boiling Point: 212.9°C at 760 mmHg
• Flash Point: 69.9°C
• PSA: 21.26000
• Density: 0.982g/cm³
• LogP: 2.74530
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 166.099379685
• Heavy Atom Count: 12
• Complexity: 114

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOCC1=CC=CC=C1OC

Technology Process of o-(Ethoxymethyl)anisole

There total 4 articles about o-(Ethoxymethyl)anisole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

ethanol (64-17-5) + ortho-anisaldehyde (135-02-4) → ethyl 2-methoxybenzyl ether (64988-06-3)

Guidance literature:

With Decaborane; at 20 ℃; for 6.5h;

DOI:10.1016/S0040-4039(99)01229-0

Reference yield:

sodium ethanolate (141-52-6) + o-Methoxybenzyl chloride (7035-02-1) → ethyl 2-methoxybenzyl ether (64988-06-3)

Guidance literature:

Reference yield:

o-Methoxybenzyl chloride (7035-02-1) → ethyl 2-methoxybenzyl ether (64988-06-3) + 2-methoxy-benzeneacetonitrile (7035-03-2)

Guidance literature:

upstream raw materials:

sodium ethanolate

o-Methoxybenzyl chloride

oxovanadium(V) ethoxydichloride

o-(trimethylsilylmethyl)benzyl alcohol