2-(diphenylphosphinoyl)-6-oxocyclohexylcarbothioic acid cyclohexylamide

Base Information

Chemical Name:2-(diphenylphosphinoyl)-6-oxocyclohexylcarbothioic acid cyclohexylamide
CAS No.:1347761-58-3
Molecular Formula:C₂₅H₃₀NO₂PS
Molecular Weight:439.558
Hs Code.:

Synonyms:2-(diphenylphosphinoyl)-6-oxocyclohexylcarbothioic acid cyclohexylamide

Suppliers and Price of 2-(diphenylphosphinoyl)-6-oxocyclohexylcarbothioic acid cyclohexylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2-(diphenylphosphinoyl)-6-oxocyclohexylcarbothioic acid cyclohexylamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 2-(diphenylphosphinoyl)-6-oxocyclohexylcarbothioic acid cyclohexylamide

There total 2 articles about 2-(diphenylphosphinoyl)-6-oxocyclohexylcarbothioic acid cyclohexylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 89358-47-4
3-(diphenylphosphoryl)cyclohexan-1-one

: 1122-82-3
isothiocyanatocyclohexane

: 1347761-58-3
2-(diphenylphosphinoyl)-6-oxocyclohexylcarbothioic acid cyclohexylamide

Guidance literature:: 3-(diphenylphosphoryl)cyclohexan-1-one; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 2h; Inert atmosphere;

isothiocyanatocyclohexane; In tetrahydrofuran; at 20 ℃; for 16h; Inert atmosphere;

With ammonium chloride; phenyl isothiocyanate; In tetrahydrofuran; Inert atmosphere; Saturated solution;
DOI:10.1016/j.tet.2011.09.093

Reference yield:

: 930-68-7
cyclohexenone

: 1347761-58-3
2-(diphenylphosphinoyl)-6-oxocyclohexylcarbothioic acid cyclohexylamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetic acid / 20 °C / Inert atmosphere

1.2: 2 h / Inert atmosphere; Reflux

2.1: potassium tert-butylate / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere

2.2: 16 h / 20 °C / Inert atmosphere

2.3: Inert atmosphere; Saturated solution

With potassium tert-butylate; acetic acid; In tetrahydrofuran; 1.1: Michael addition;
DOI:10.1016/j.tet.2011.09.093