6-methyl-2-(4'-bromophenyl)-3-dimethylaminomethylimidazo[1,2-a]pyridine

Base Information

• Chemical Name: 6-methyl-2-(4'-bromophenyl)-3-dimethylaminomethylimidazo[1,2-a]pyridine
• CAS No.: 274263-97-7
• Molecular Formula: C₁₇H₁₈BrN₃
• Molecular Weight: 344.254
• Mol file: 274263-97-7.mol

Synonyms:6-methyl-2-(4'-bromophenyl)-3-dimethylaminomethylimidazo[1,2-a]pyridine

Chemical Property of 6-methyl-2-(4'-bromophenyl)-3-dimethylaminomethylimidazo[1,2-a]pyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-methyl-2-(4'-bromophenyl)-3-dimethylaminomethylimidazo[1,2-a]pyridine

There total 1 articles about 6-methyl-2-(4'-bromophenyl)-3-dimethylaminomethylimidazo[1,2-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + dimethyl amine (124-40-3) + 6-methyl-2-(4'-bromophenyl)imidazo[1,2-a]pyridine (1023-01-4) → 6-methyl-2-(4'-bromophenyl)-3-dimethylaminomethylimidazo[1,2-a]pyridine (274263-97-7)

Guidance literature:

With acetic acid; In water; at 55 ℃; for 24h;

DOI:10.1002/(SICI)1099-1344(20000330)43:4<385::AID-JLCR325>3.0.CO;2-K

Reference yield: 95.0%

6-methyl-2-(4'-bromophenyl)-3-dimethylaminomethylimidazo[1,2-a]pyridine (274263-97-7) + methyl iodide (74-88-4) → 6-methyl-2-(4'-bromophenyl)-3-dimethylaminomethylimidazo[1,2-a]pyridinyl methiodide

Guidance literature:

In benzene; at 20 ℃; for 72h;

DOI:10.1002/(SICI)1099-1344(20000330)43:4<385::AID-JLCR325>3.0.CO;2-K

Reference yield:

6-methyl-2-(4'-bromophenyl)-3-dimethylaminomethylimidazo[1,2-a]pyridine (274263-97-7) → 6-methyl-2-(4'-bromophenyl)imidazo[1,2-a]pyridine-3-acetic acid (274264-03-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent / benzene / 72 h / 20 °C

2: 70 percent / ethanol; H₂O / 24 h / Heating

3: 85 percent / conc. HCl / acetic acid / 16 h

With hydrogenchloride; In ethanol; water; acetic acid; benzene; 1: Methylation / 2: Substitution / 3: Hydrolysis;

DOI:10.1002/(SICI)1099-1344(20000330)43:4<385::AID-JLCR325>3.0.CO;2-K

upstream raw materials:

formaldehyd

dimethyl amine

6-methyl-2-(4'-bromophenyl)imidazo[1,2-a]pyridine

Downstream raw materials:

6-methyl-2-(4'-bromophenyl)imidazo[1,2-a]pyridine-3-acetonitrile

6-methyl-2-(4'-bromophenyl)imidazo[1,2-a]pyridine-3-acetic acid