Methyl 1-aminocyclopropanecarboxylate hydrochloride

Base Information

• Chemical Name: Methyl 1-aminocyclopropanecarboxylate hydrochloride
• CAS No.: 72784-42-0
• Molecular Formula: C5H9NO2^.HCl
• Molecular Weight: 151.593
• Hs Code.: 2922499990
• European Community (EC) Number: 831-734-7
• DSSTox Substance ID: DTXSID50509210
• Mol file: 72784-42-0.mol

Synonyms:72784-42-0;Methyl 1-aminocyclopropanecarboxylate hydrochloride;1-Aminocyclopropane-1-carboxylic acid methyl ester hydrochloride;methyl 1-aminocyclopropane-1-carboxylate hydrochloride;Methyl 1-aminocyclopropanecarboxylate HCl;Methyl 1-aminocyclopropanecarboxylate, HCl;MFCD00078879;methyl 1-aminocyclopropane-1-carboxylate;hydrochloride;Methyl 1-aminocyclopropane-1-carboxylate HCl;1,1-Accp(ome);CHSDCWKLSHPKFY-UHFFFAOYSA-N;ACPC-OMe HCl;H-Acpc-OEt.HCl;Cyclopropanecarboxylic acid, 1-amino-, methyl ester, hydrochloride;SCHEMBL233616;DTXSID50509210;AKOS005145950;AC-7454;CS-W008219;GS-3859;HY-W008219;PB47476;AM804291;PD196541;SY017503;FT-0607342;EN300-122695;Methyl1-aminocyclopropanecarboxylatehydrochloride;A837617;methyl-1-aminocyclopropanecarboxylate hydrochloride;methyl 1-amino-cyclopropane-carboxylate hydrochloride;methyl 1-aminocyclopropane carboxylate hydrochloride;1-aminocyclopropane-1-carboxylic acid methyl ester HCl;methyl l-aminocyclopropane-1-carboxylate hydrochloride;Z1552027431;1-Amino-cyclopropane-carboxylicacidmethylester hydrochloride;1-Aminocyclopropanecarboxylic acid methyl ester hydrochloride;1-amino-cyclopropanecarboxylic acid methyl ester hydrochloride;1-Aminocyclopropane-1-carboxylic Acid Methyl Ester, Hydrochloride;Methyl 1-aminocyclopropane-1-carboxylate--hydrogen chloride (1/1)

Chemical Property of Methyl 1-aminocyclopropanecarboxylate hydrochloride

Chemical Property:

• Appearance/Colour: White Crystalline Solid
• Vapor Pressure: 7.4mmHg at 25°C
• Melting Point: 185-186 °C
• Boiling Point: 136.4 °C at 760 mmHg
• Flash Point: 11.8 °C
• PSA: 52.32000
• LogP: 0.35100
• Storage Temp.: 2-8°C
• Solubility.: Methanol, Water
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 151.0400063
• Heavy Atom Count: 9
• Complexity: 118

Purity/Quality:

97% ^*data from raw suppliers

1-Aminocyclopropane-1-carboxylic Acid Methyl Ester, Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C1(CC1)N.Cl
• Uses: Methyl 1-aminocyclopropanecarboxylate hydrochloride is used in pharmaceutical compositions.

Technology Process of Methyl 1-aminocyclopropanecarboxylate hydrochloride

There total 6 articles about Methyl 1-aminocyclopropanecarboxylate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + aminocyclopropane-1-carboxylic acid (22059-21-8) → methyl 1-aminocyclopropane-1-carboxylate hydrochloride (72784-42-0)

Guidance literature:

methanol; With acetyl chloride;

aminocyclopropane-1-carboxylic acid; Reflux;

Reference yield: 94.0%

→ methyl 1-aminocyclopropane-1-carboxylate hydrochloride (72784-42-0)

Guidance literature:

With thionyl chloride; at 0 - 20 ℃; for 16h;

Reference yield: 58.0%

α-amino-cyclopropanecarboxylic acid hydrochloride (68781-13-5) → methyl 1-aminocyclopropane-1-carboxylate hydrochloride (72784-42-0)

Guidance literature:

With hydrogenchloride; In methanol; at 0 - 65 ℃; for 4h;

DOI:10.1055/s-0034-1380434

upstream raw materials:

methanol

aminocyclopropane-1-carboxylic acid

1-(Benzhydrylidene-amino)-cyclopropanecarboxylic acid methyl ester

methyl 1-[[(tert-butoxy)carbonyl]amino]cyclopropane-1-carboxylate

Downstream raw materials:

1-{[1-Phenyl-meth-(E)-ylidene]-amino}-cyclopropanecarboxylic acid methyl ester

aminocyclopropane-1-carboxylic acid

methyl 1-aminocyclopropane-1-carboxylate

1-Phenylamino-cyclopropanecarboxylic acid methyl ester