TRIMETHYLSILYL ISOBUTYRATE

Base Information

• Chemical Name: TRIMETHYLSILYL ISOBUTYRATE
• CAS No.: 16883-61-7
• Molecular Formula: C7H16O2Si
• Molecular Weight: 160.288
• Hs Code.: 2931900090
• Mol file: 16883-61-7.mol

Synonyms:Isobutyricacid, trimethylsilyl ester (8CI);

Chemical Property of TRIMETHYLSILYL ISOBUTYRATE

Chemical Property:

• Appearance/Colour: clear colorless liquid
• Vapor Pressure: 8.16mmHg at 25°C
• Refractive Index: 1.404
• Boiling Point: 134.249 °C at 760 mmHg
• Flash Point: 29.242 °C
• PSA: 26.30000
• Density: 0.873 g/cm³
• LogP: 2.02050
• Storage Temp.: 0-6°C

Purity/Quality:

98%min ^*data from raw suppliers

TRIMETHYLSILYL ISOBUTYRATE 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of TRIMETHYLSILYL ISOBUTYRATE

There total 7 articles about TRIMETHYLSILYL ISOBUTYRATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2-methyl-1-(trimethylsilyl)propan-1-one (56583-93-8) + diazodiphenylmethane (908093-98-1) → benzophenone (119-61-9) + trimethylsilyl isobutyrate (16883-61-7)

Guidance literature:

With 5,10,15,20-tetrakisphenylporphyrin; oxygen; In benzene; for 0.166667h; Ambient temperature; Irradiation;

DOI:10.1021/jo00136a018

Reference yield:

trimethylsilyl 2-<(trimethylsiloxy)carbonyl>-2-propanesulfinate (75669-59-9) → Hexamethyldisiloxane (107-46-0) + trimethylsilyl isobutyrate (16883-61-7)

Guidance literature:

at 120 ℃; for 4h; Product distribution;

Reference yield:

chloro-trimethyl-silane (75-77-4) + isobutyric Acid (79-31-2) → trimethylsilyl isobutyrate (16883-61-7)

Guidance literature:

With sodium hydride; In diethyl ether; Heating;

DOI:10.1016/S0022-328X(00)90476-5

upstream raw materials:

chloro-trimethyl-silane

isobutyric acid sodium salt

isobutyric Acid

trimethylsilyl 2-<(trimethylsiloxy)carbonyl>-2-propanesulfinate

Downstream raw materials:

4'-chloro-2-methyl-2'-nitropropananilide

2-methyl-N-(2-nitrophenyl)propanamide

Hexamethyldisiloxane

2-Triphenylphosphoranyliden-4-methyl-pentan-3-on

Refernces

• 1、 Kotowska, Urszula,Isidorov, Valery A.. "Partition coefficients of ketones, phenols, aliphatic and aromatic acids, and esters in n-hexane/nitromethane". scheme or table. p. 813 - 824. Retrieved 2012/03/27.
• 2、 Sekiguchi, Akira,Kabe, Yoshio,Ando, Wataru. "Dye-Sensitized Photooxidation of Silyl Diazo Compounds. Intramolecular Oxygen Transfer of Carbonyl Oxides". . p. 2900 - 2903. Retrieved 2007/10/02.