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pyridin-2-ylmethoxybenzene

Base Information
  • Chemical Name:pyridin-2-ylmethoxybenzene
  • CAS No.:104294-19-1
  • Molecular Formula:C12H11NO
  • Molecular Weight:185.225
  • Hs Code.:
pyridin-2-ylmethoxybenzene

Synonyms:pyridin-2-ylmethoxybenzene

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Chemical Property of pyridin-2-ylmethoxybenzene
Chemical Property:
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Technology Process of pyridin-2-ylmethoxybenzene

There total 7 articles about pyridin-2-ylmethoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With sodium hydroxide; In water; toluene;
Guidance literature:
With trans-RuCl2((S,S)-skewphos)((R,R)-dpen); hydrogen; sodium isopropylate; In isopropyl alcohol; at 20 ℃; for 24h; under 3040.2 Torr; enantioselective reaction; Autoclave;
DOI:10.1021/jacs.6b12254
Guidance literature:
Multi-step reaction with 2 steps
1.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.75 h / -78 °C / Inert atmosphere
1.2: 48 h / -78 - 20 °C / Inert atmosphere
2.1: sodium isopropylate; hydrogen; trans-RuCl2((S,S)-skewphos)((R,R)-dpen) / isopropyl alcohol / 24 h / 20 °C / 3040.2 Torr / Autoclave
With trans-RuCl2((S,S)-skewphos)((R,R)-dpen); hydrogen; sodium isopropylate; lithium hexamethyldisilazane; In tetrahydrofuran; isopropyl alcohol;
DOI:10.1021/jacs.6b12254
upstream raw materials:

2-chloromethylpyridine

sodium phenoxide

triazolopyridine

phenol

Downstream raw materials:

C16H17NO2

C17H21NO2

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