N-(2-Chloroethyl)phthalimide

Base Information

Chemical Name:N-(2-Chloroethyl)phthalimide
CAS No.:6270-06-0
Molecular Formula:C10H8ClNO2
Molecular Weight:209.632
Hs Code.:2925190090
European Community (EC) Number:634-709-7
NSC Number:44378,33824
DSSTox Substance ID:DTXSID90283860
Nikkaji Number:J422.071D
Wikidata:Q82018591
Mol file:6270-06-0.mol

Synonyms:6270-06-0;N-(2-Chloroethyl)phthalimide;2-(2-chloroethyl)isoindoline-1,3-dione;2-(2-chloroethyl)-1H-isoindole-1,3(2H)-dione;2-(2-chloroethyl)isoindole-1,3-dione;2-(2-Chloroethyl-d4)-;2-(2-Chloroethyl)-1H-isoindole-1,3-dione;NSC33824;1H-Isoindole-1,3(2H)-dione, 2-(2-chloroethyl)-;N-(2-chloroethyl) phthalimide;N-(2-chloroethyl)-phthalimide;SCHEMBL2296434;DTXSID90283860;ZPHGARLYQHMNTB-UHFFFAOYSA-N;NSC44378;AM9836;BBL036223;MFCD00129356;NSC-33824;NSC-44378;STK503411;AKOS004117973;CS-W015140;SB64091;N-(2-Chloroethyl)phthalimide, >=98%;AS-54918;2-(2-Chloro-ethyl)-isoindole-1,3-dione;FT-0664688;FT-0664689;W11053;A833933

Suppliers and Price of N-(2-Chloroethyl)phthalimide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(2-Chloroethyl)-1H-isoindole-1,3-dione
100mg
$ 155.00

SynQuest Laboratories
2-(2-Chloroethyl)-1H-isoindole-1,3(2H)-dione
1 g
$ 152.00

Sigma-Aldrich
N-(2-Chloroethyl)phthalimide ≥98%
5g
$ 61.00

Medical Isotopes, Inc.
2-(2-Chloroethyl)-1H-isoindole-1,3-dione
100 mg
$ 640.00

Matrix Scientific
2-(2-Chloroethyl)-1H-isoindole-1,3(2H)-dione
500mg
$ 126.00

Crysdot
2-(2-Chloroethyl)isoindoline-1,3-dione 95+%
10g
$ 486.00

Chemenu
2-(2-Chloroethyl)isoindoline-1,3-dione 95%
10g
$ 459.00

Biosynth Carbosynth
2-(2-Chloroethyl)-1H-isoindole-1,3(2H)-dione
2 g
$ 104.00

Biosynth Carbosynth
2-(2-Chloroethyl)-1H-isoindole-1,3(2H)-dione
10 g
$ 300.00

Biosynth Carbosynth
2-(2-Chloroethyl)-1H-isoindole-1,3(2H)-dione
5 g
$ 200.00

Total 22 raw suppliers

Chemical Property of N-(2-Chloroethyl)phthalimide

Chemical Property:

Vapor Pressure:0.000192mmHg at 25°C
Melting Point:82-84 °C(lit. )
Refractive Index:1.599
Boiling Point:328.2 °C at 760 mmHg
PKA:-2.32±0.20(Predicted)
Flash Point:152.3 °C
PSA：37.38000
Density:1.383 g/cm³
LogP:1.45930
Storage Temp.:Refrigerator
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:209.0243562
Heavy Atom Count:14
Complexity:243

Purity/Quality:

97% ^*data from raw suppliers

2-(2-Chloroethyl)-1H-isoindole-1,3-dione ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)N(C2=O)CCCl
Uses N-(2-Chloroethyl)phthalimide may be used in the preparation of 1-[(dialkylamino)alkyl]-1,8-napthyridin-2(1H)ones and were evaluated for the inhibition of gastric acid secretion invivo.

Technology Process of N-(2-Chloroethyl)phthalimide

There total 3 articles about N-(2-Chloroethyl)phthalimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 3891-07-4
N-(2-Hydroxyethyl)phthalimide

: 98-88-4
benzoyl chloride

: 6656-84-4
2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl benzoate

: 6270-06-0
N-(2-chlroethyl)phthalimide

Guidance literature:: With 2,3-diethyl-2-cyclopropen-1-one; In tert-butyl methyl ether; at 40 ℃; for 24h;
DOI:10.1021/acs.orglett.8b01023

Reference yield:

: 80-41-1
2-chloroethyl tosylate

: 1074-82-4
potassium phtalimide

: 607-26-1
N,N'-ethylenediphthalimide

: 6270-06-0
N-(2-chlroethyl)phthalimide

Guidance literature:: With xylene; unter Abdestillieren des Loesungsmittels und weiteren Erhitzen bis auf 200grad;

Reference yield:

: 85-44-9
phthalic anhydride

: 6270-06-0
N-(2-chlroethyl)phthalimide

Guidance literature:: Multi-step reaction with 2 steps

2: phosphorus (V)-chloride

With phosphorus pentachloride;
DOI:10.1021/ja01281a504