3-(3-tert-butyl-4-methoxy-5-(methoxycarbonyl)phenylamino)propanoic acid

Base Information

Chemical Name:3-(3-tert-butyl-4-methoxy-5-(methoxycarbonyl)phenylamino)propanoic acid
CAS No.:1132941-85-5
Molecular Formula:C₁₆H₂₃NO₅
Molecular Weight:309.362
Hs Code.:

Synonyms:3-(3-tert-butyl-4-methoxy-5-(methoxycarbonyl)phenylamino)propanoic acid

Suppliers and Price of 3-(3-tert-butyl-4-methoxy-5-(methoxycarbonyl)phenylamino)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 3 raw suppliers

Chemical Property of 3-(3-tert-butyl-4-methoxy-5-(methoxycarbonyl)phenylamino)propanoic acid

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

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Technology Process of 3-(3-tert-butyl-4-methoxy-5-(methoxycarbonyl)phenylamino)propanoic acid

There total 4 articles about 3-(3-tert-butyl-4-methoxy-5-(methoxycarbonyl)phenylamino)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1132941-02-6
methyl 5-amino-3-tert-butyl-2-methoxybenzoate

: 79-10-7
acrylic acid

: 1132941-85-5
3-(3-tert-butyl-4-methoxy-5-(methoxycarbonyl)phenylamino)propanoic acid

Guidance literature:: In toluene; for 24h; Reflux;
DOI:10.1021/acs.jmedchem.7b01630

Reference yield:

: 1132941-00-4
3-tert-butyl-2-methoxy-5-nitrobenzoate

: 1132941-85-5
3-(3-tert-butyl-4-methoxy-5-(methoxycarbonyl)phenylamino)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: iron; ammonium chloride / methanol; water / 1 h / Reflux

2: toluene / 24 h / Reflux

With iron; ammonium chloride; In methanol; water; toluene;
DOI:10.1021/acs.jmedchem.7b01630

Reference yield:

: 15018-03-8
methyl 3,5‐di‐tert-butyl‐2‐hydroxybenzoate

: 1132941-85-5
3-(3-tert-butyl-4-methoxy-5-(methoxycarbonyl)phenylamino)propanoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: nitric acid; acetic acid / 2.5 h / 20 °C

2: potassium carbonate / acetone / Reflux

3: iron; ammonium chloride / methanol; water / 1 h / Reflux

4: toluene / 24 h / Reflux

With nitric acid; iron; potassium carbonate; ammonium chloride; acetic acid; In methanol; water; acetone; toluene;
DOI:10.1021/acs.jmedchem.7b01630