4-[(TRIMETHYLSILYL)OXY]-BENZOIC ACID TRIMETHYLSILYL ESTER

Base Information

• Chemical Name: 4-[(TRIMETHYLSILYL)OXY]-BENZOIC ACID TRIMETHYLSILYL ESTER
• CAS No.: 2078-13-9
• Molecular Formula: C13H22 O3 Si2
• Molecular Weight: 282.487
• Hs Code.: 2931900090
• Mol file: 2078-13-9.mol

Synonyms:Benzoicacid, p-(trimethylsiloxy)-, trimethylsilyl ester (6CI,7CI,8CI); Silanol,trimethyl-, p-(trimethylsiloxy)benzoate (8CI); Trimethylsilylp-(trimethylsilyloxy)benzoate

Chemical Property of 4-[(TRIMETHYLSILYL)OXY]-BENZOIC ACID TRIMETHYLSILYL ESTER

Chemical Property:

• Vapor Pressure: 0.00635mmHg at 25°C
• Refractive Index: 1.47
• Boiling Point: 271.7°Cat760mmHg
• Flash Point: 98.2°C
• PSA: 35.53000
• Density: 0.978g/cm³
• LogP: 3.89200

Purity/Quality:

98%min ^*data from raw suppliers

4-[(TRIMETHYLSILYL)OXY]-BENZOIC ACID TRIMETHYLSILYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-[(TRIMETHYLSILYL)OXY]-BENZOIC ACID TRIMETHYLSILYL ESTER

There total 6 articles about 4-[(TRIMETHYLSILYL)OXY]-BENZOIC ACID TRIMETHYLSILYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) + 4-hydroxy-benzoic acid (99-96-7) → 4-[(trimethylsilyl)oxy]benzoic acid trimethylsilyl ester (2078-13-9)

Guidance literature:

With iodine; In neat (no solvent); at 20 ℃; for 0.67h; Green chemistry;

DOI:10.1016/j.tet.2016.08.003

Reference yield: 90.0%

chloro-trimethyl-silane (75-77-4) + 4-hydroxy-benzoic acid (99-96-7) → 4-[(trimethylsilyl)oxy]benzoic acid trimethylsilyl ester (2078-13-9)

Guidance literature:

With triethylamine; In toluene; for 2h; Heating;

Reference yield:

N,O-bis-(trimethylsilyl)-acetamide (10416-59-8) + 4-hydroxy-benzoic acid (99-96-7) → 4-[(trimethylsilyl)oxy]benzoic acid trimethylsilyl ester (2078-13-9)

Guidance literature:

With pyridine; at 20 ℃; for 1h;

DOI:10.1021/jf703701n

upstream raw materials:

chloro-trimethyl-silane

4-hydroxy-benzoic acid

1,1,1,3,3,3-hexamethyl-disilazane

1,1,1,2,2,2-hexamethyldisilane

Downstream raw materials:

4-(trimethylsilyloxy)benzoyl chloride

trimethylsilyl fluoride

(CH₃)3SiOC(O)C₆H₄OSO₂C₄F₉

4-(Perfluorbutansulfonyloxy)-benzoesaeure