METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACID

Base Information

• Chemical Name: METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACID
• CAS No.: 167300-06-3
• Molecular Formula: C10H10 O4
• Molecular Weight: 194.187
• Hs Code.: 2918990090
• Mol file: 167300-06-3.mol

Synonyms:3-(Methoxycarbonyl)-4-methylbenzoicacid

Chemical Property of METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACID

Chemical Property:

• Vapor Pressure: 1.7E-05mmHg at 25°C
• Refractive Index: 1.55
• Boiling Point: 349.9°Cat760mmHg
• PKA: 4.00±0.10(Predicted)
• Flash Point: 140.1°C
• PSA: 63.60000
• Density: 1.243g/cm³
• LogP: 1.47980
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98% ^*data from raw suppliers

3-(Methoxycarbonyl)-4-methylbenzoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACID

There total 4 articles about METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

methyl 5-formyl-2-methylbenzoate (675148-96-6) → 3-(methoxycarbonyl)-4-methylbenzoic acid (167300-06-3)

Guidance literature:

With Oxone; In N,N-dimethyl-formamide; at 20 ℃; for 18h;

Reference yield:

methanol (67-56-1) + BF4(1-)*C8H7N2O2(1+) + carbon monoxide (201230-82-2) → 3-(methoxycarbonyl)-4-methylbenzoic acid (167300-06-3)

Guidance literature:

palladium diacetate; at 20 ℃; for 1.25h;

Reference yield:

5-formyl-2-methylbenzoic acid (105650-34-8) → 3-(methoxycarbonyl)-4-methylbenzoic acid (167300-06-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sulfuric acid / 2 h / 100 °C / Sealed tube

1.2: 1 h

2.1: Oxone / N,N-dimethyl-formamide / 18 h / 20 °C

With Oxone; sulfuric acid; In N,N-dimethyl-formamide;

upstream raw materials:

methanol

carbon monoxide

3-bromo-4-methylbenzoic acid

methyl chloroformate

Downstream raw materials:

4-methyl-isophthalic acid 1-tert-butyl ester 3-methyl ester

ethyl 5-chloro-1-[2'-hydroxy-3'-(methyloxy)-4-biphenylyl]-3-{[({4-methyl-3-[(methyloxy)carbonyl]phenyl}amino)carbonyl]amino}-1H-pyrrole-2-carboxylate

5-{6-chloro-5-[2'-hydroxy-3'-(methyloxy)-4-biphenylyl]-2,4-dioxo-1,2,4,5-tetrahydro-3H-pyrrolo[3,2-d]pyrimidin-3-yl}-2-methylbenzoic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 167300-06-3 METHYL-2-METHYL-5-CARBOXYLICBENZOIC ACID

Send

Send

Metric Ton KG G Pound L ML

Send

Send