diethyl α-(chloromethyl)-α-<(trimethylsilyl)oxy>benzylphosphonate

Base Information Edit

Chemical Name:diethyl α-(chloromethyl)-α-<(trimethylsilyl)oxy>benzylphosphonate
CAS No.:78610-05-6
Molecular Formula:C₁₅H₂₆ClO₄PSi
Molecular Weight:364.881
Hs Code.:
Mol file:78610-05-6.mol

Synonyms:diethyl α-(chloromethyl)-α-<(trimethylsilyl)oxy>benzylphosphonate

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Chemical Property of diethyl α-(chloromethyl)-α-<(trimethylsilyl)oxy>benzylphosphonate Edit

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Technology Process of diethyl α-(chloromethyl)-α-<(trimethylsilyl)oxy>benzylphosphonate

There total 2 articles about diethyl α-(chloromethyl)-α-<(trimethylsilyl)oxy>benzylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 31675-43-1
diethyl 1-phenyl-1-(trimethylsiloxy)methanephosphonate

: 78610-05-6
diethyl α-(chloromethyl)-α-<(trimethylsilyl)oxy>benzylphosphonate

Guidance literature:: Multi-step reaction with 2 steps

1: LDA / tetrahydrofuran / 0.5 h / -78 °C

2: 0.5 h / -78 °C

With lithium diisopropyl amide; In tetrahydrofuran;
DOI:10.1021/jo00333a018