5-ethoxycarbonyl-5-ethyl-2-phenyl<1,2,4>triazolidine-3-thione

Base Information

• Chemical Name: 5-ethoxycarbonyl-5-ethyl-2-phenyl<1,2,4>triazolidine-3-thione
• CAS No.: 220437-88-7
• Molecular Formula: C₁₃H₁₇N₃O₂S
• Molecular Weight: 279.363
• Mol file: 220437-88-7.mol

Synonyms:5-ethoxycarbonyl-5-ethyl-2-phenyl<1,2,4>triazolidine-3-thione

Chemical Property of 5-ethoxycarbonyl-5-ethyl-2-phenyl<1,2,4>triazolidine-3-thione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-ethoxycarbonyl-5-ethyl-2-phenyl<1,2,4>triazolidine-3-thione

There total 3 articles about 5-ethoxycarbonyl-5-ethyl-2-phenyl<1,2,4>triazolidine-3-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

2-phenylhydrazono-butyric acid ethyl ester (167479-51-8) + potassium thioacyanate (333-20-0) → 5-ethoxycarbonyl-5-ethyl-2-phenyl<1,2,4>triazolidine-3-thione (220437-88-7)

Guidance literature:

In formic acid; at 50 ℃; for 18h;

DOI:10.3987/com-98-s(h)35

Reference yield:

Ethyl 2-oxobutanoate (15933-07-0) → 5-ethoxycarbonyl-5-ethyl-2-phenyl<1,2,4>triazolidine-3-thione (220437-88-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 77 percent / acetic acid / ethanol

2: 25 percent / formic acid / 18 h / 50 °C

With acetic acid; In formic acid; ethanol;

DOI:10.3987/com-98-s(h)35

Reference yield:

phenylhydrazine (100-63-0) → 5-ethoxycarbonyl-5-ethyl-2-phenyl<1,2,4>triazolidine-3-thione (220437-88-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 77 percent / acetic acid / ethanol

2: 25 percent / formic acid / 18 h / 50 °C

With acetic acid; In formic acid; ethanol;

DOI:10.3987/com-98-s(h)35

upstream raw materials:

2-phenylhydrazono-butyric acid ethyl ester

potassium thioacyanate

Ethyl 2-oxobutanoate

phenylhydrazine