N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-3-formylbenzeneacetamide

Base Information

• Chemical Name: N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-3-formylbenzeneacetamide
• CAS No.: 333389-48-3
• Molecular Formula: C₂₀H₂₁N₃O₃S₂
• Molecular Weight: 415.537
• Mol file: 333389-48-3.mol

Synonyms:N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-3-formylbenzeneacetamide

Chemical Property of N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-3-formylbenzeneacetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-3-formylbenzeneacetamide

There total 1 articles about N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-3-formylbenzeneacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

oxalyl dichloride (79-37-8) + 2-(3-formylphenyl)acetic acid (34956-29-1) + sodium hydrogencarbonate (144-55-8) + 2-amino-5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-thiazole (224436-97-9) → N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-3-formylbenzeneacetamide (333389-48-3)

Guidance literature:

With triethylamine; In dichloromethane;

Reference yield:

N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-3-formylbenzeneacetamide (333389-48-3) → 3-(aminomethyl)-N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]benzeneacetamide

Guidance literature:

With triethylsilane; trifluoroacetic acid; In dichloromethane; acetonitrile;

Reference yield:

N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-3-formylbenzeneacetamide (333389-48-3) + 3-amino-2,2-dimethylpropan-1-ol (26734-09-8) + sodium hydrogencarbonate (144-55-8) → N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-3-[[(3-hydroxy-2,2-dimethylpropyl)amino]methyl]benzeneacetamide

Guidance literature:

With ammonium hydroxide; sodium tris(acetoxy)borohydride; acetic acid; In tetrahydrofuran; methanol; ethyl acetate;

upstream raw materials:

oxalyl dichloride

2-(3-formylphenyl)acetic acid

sodium hydrogencarbonate

2-amino-5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-thiazole