1-Boc-4-dimethylcarbamoylpiperidine

Base Information

Chemical Name:1-Boc-4-dimethylcarbamoylpiperidine
CAS No.:254905-58-3
Molecular Formula:C₁₃H₂₄N₂O₃
Molecular Weight:256.345
Hs Code.:2933399090
DSSTox Substance ID:DTXSID30452250
Wikidata:Q82272753
Mol file:254905-58-3.mol

Synonyms:254905-58-3;1-BOC-4-DIMETHYLCARBAMOYLPIPERIDINE;Tert-butyl 4-(dimethylcarbamoyl)piperidine-1-carboxylate;Octafoniumchloride;SCHEMBL1087013;DTXSID30452250;VRVUOIHXJJWKIY-UHFFFAOYSA-N;4-(dimethylcarbamoyl)piperidine-1-carboxylic acid tert-butyl ester;MFCD07776586;AKOS000164112;SB43441;AM807716;BS-24881;CS-0188262;FT-0652607;EN300-3550397;A817876;tert-butyl-4-(dimethylcarbamoyl)piperidine-1-carboxylate;Tert-butyl4-(dimethylcarbamoyl)piperidine-1-carboxylate;Z100642480;4-dimethylcarbamoyl-piperidine-1-carboxylic acid tert-butyl ester;4-[dimethylamino(oxo)methyl]-1-piperidinecarboxylic acid tert-butyl ester

Suppliers and Price of 1-Boc-4-dimethylcarbamoylpiperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl4-(dimethylcarbamoyl)piperidine-1-carboxylate 97%
5g
$ 671.00

Chemenu
tert-Butyl4-(dimethylcarbamoyl)piperidine-1-carboxylate 97%
5g
$ 634.00

Alichem
tert-Butyl4-(dimethylcarbamoyl)piperidine-1-carboxylate
5g
$ 1247.40

Alichem
tert-Butyl4-(dimethylcarbamoyl)piperidine-1-carboxylate
1g
$ 423.72

Total 12 raw suppliers

Chemical Property of 1-Boc-4-dimethylcarbamoylpiperidine

Chemical Property:

PSA：49.85000
LogP:1.65960
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:256.17869263
Heavy Atom Count:18
Complexity:313

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl4-(dimethylcarbamoyl)piperidine-1-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(CC1)C(=O)N(C)C

Technology Process of 1-Boc-4-dimethylcarbamoylpiperidine

There total 4 articles about 1-Boc-4-dimethylcarbamoylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 506-59-2
N,N-dimethylammonium chloride

: 84358-13-4,174286-31-8
N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid

: 254905-58-3
4-(dimethylcarbamoyl)piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: With triethylamine; HATU; In dichloromethane; at 20 ℃;

Reference yield: 77.0%

: 84358-13-4,174286-31-8
N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid

: 124-40-3
dimethyl amine

: 254905-58-3
4-(dimethylcarbamoyl)piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid; With triethylamine; 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 50 ℃; for 0.5h;

dimethyl amine; In tetrahydrofuran; at 20 ℃; for 18h;
DOI:10.1016/j.ejmech.2015.07.029