3,5-Bis(4-chlorophenyl)-1-phenyl-1h-pyrazole

Base Information

Chemical Name:3,5-Bis(4-chlorophenyl)-1-phenyl-1h-pyrazole
CAS No.:27293-96-5
Molecular Formula:C21H14 Cl2 N2
Molecular Weight:365.262
Hs Code.:
NSC Number:133081
DSSTox Substance ID:DTXSID30299829
Nikkaji Number:J3.017.709F
Wikidata:Q82042499

Synonyms:3,5-bis(4-chlorophenyl)-1-phenyl-1h-pyrazole;27293-96-5;NSC133081;SCHEMBL9051206;DTXSID30299829;NSC-133081

Suppliers and Price of 3,5-Bis(4-chlorophenyl)-1-phenyl-1h-pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 3,5-Bis(4-chlorophenyl)-1-phenyl-1h-pyrazole

Chemical Property:

Vapor Pressure:1.88E-10mmHg at 25°C
Boiling Point:521.4°Cat760mmHg
Flash Point:269.1°C
Density:1.25g/cm³
XLogP3:6.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:364.0534038
Heavy Atom Count:25
Complexity:410

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)N2C(=CC(=N2)C3=CC=C(C=C3)Cl)C4=CC=C(C=C4)Cl

Technology Process of 3,5-Bis(4-chlorophenyl)-1-phenyl-1h-pyrazole

There total 6 articles about 3,5-Bis(4-chlorophenyl)-1-phenyl-1h-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 57845-06-4
3-(4-chlorophenyl)-5-(4-chlorophenyl)-1-phenyl-2-pyrazoline

: 27293-96-5
3,5-bis-(4-chloro-phenyl)-1-phenyl-1H-pyrazole

Guidance literature:: With hydrogen tetrachloroaurate(III) tetrahydrate; oxygen; acetic acid; at 50 ℃;
DOI:10.1080/00304940902956119

Reference yield: 89.0%

: 1679-18-1
4-Chlorophenylboronic acid

: 80967-19-7
3-(methylthio)-1-phenyl-3-(prop-2-yn-1-ylthio)prop-2-en-1-one

: 100-63-0
phenylhydrazine

: 27293-96-5
3,5-bis-(4-chloro-phenyl)-1-phenyl-1H-pyrazole

Guidance literature:: 4-Chlorophenylboronic acid; 3-(methylthio)-1-phenyl-3-(prop-2-yn-1-ylthio)prop-2-en-1-one; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; caesium carbonate; In tetrahydrofuran; at 50 ℃; for 2h; Inert atmosphere;

phenylhydrazine; With potassium tert-butylate; In tert-butyl alcohol; for 12h; regioselective reaction; Reflux;
DOI:10.1016/j.tetlet.2011.08.168