Benzeneacetic acid, 4-(2-hydroxy-2-methylpropyl)- (9CI)

Base Information

Chemical Name:Benzeneacetic acid, 4-(2-hydroxy-2-methylpropyl)- (9CI)
CAS No.:861448-74-0
Molecular Formula:C12H16 O3
Molecular Weight:208.25364
Hs Code.:
Mol file:861448-74-0.mol

Synonyms:Benzeneacetic acid, 4-(2-hydroxy-2-methylpropyl)- (9CI)

Suppliers and Price of Benzeneacetic acid, 4-(2-hydroxy-2-methylpropyl)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(2-Hydroxy-2-methylpropyl)-benzeneaceticAcid-d6
100mg
$ 1320.00

TRC
4-(2-Hydroxy-2-methylpropyl)-benzeneaceticAcid-d6
10mg
$ 165.00

Medical Isotopes, Inc.
4-(2-Hydroxy-2-methylpropyl)-benzeneaceticAcid-d6
100 mg
$ 2200.00

Total 0 raw suppliers

Chemical Property of Benzeneacetic acid, 4-(2-hydroxy-2-methylpropyl)- (9CI)

Chemical Property:

PSA：57.53000
LogP:1.62710
Storage Temp.:Refrigerator
Solubility.:Dichloroemthane, Ethyl Acetate, Methanol

Purity/Quality:: 4-(2-Hydroxy-2-methylpropyl)-benzeneaceticAcid-d6 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Reactant in the preparation of β-3 Adrenergic Receptor Agonists.

Technology Process of Benzeneacetic acid, 4-(2-hydroxy-2-methylpropyl)- (9CI)

There total 9 articles about Benzeneacetic acid, 4-(2-hydroxy-2-methylpropyl)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 88594-72-3
[4-(2-oxopropyl)phenyl]acetic acid

: 75-16-1
methylmagnesium bromide

: 861448-74-0
[4-(2-hydroxy-2-methylpropyl)phenyl]acetic acid

Guidance literature:: [4-(2-oxopropyl)phenyl]acetic acid; methylmagnesium bromide; In tetrahydrofuran; diethyl ether; at 8 - 20 ℃; for 5.5h; Inert atmosphere;

With water; In tetrahydrofuran; diethyl ether; at 5 ℃;
DOI:10.1021/op1001462

Reference yield: 54.0%

: 17833-56-6
ester monomethylique de l'acide p-phenylene diacetique

: 75-16-1
methylmagnesium bromide

: 861448-74-0
[4-(2-hydroxy-2-methylpropyl)phenyl]acetic acid

Guidance literature:: In tetrahydrofuran; toluene; at 10 ℃;
DOI:10.1039/c1gc15694b

Reference yield:

: 113520-36-8
2-(4-(2-ethoxy-2-oxoethyl)phenyl)acetic acid

: 676-58-4
methylmagnesium chloride

: 861448-74-0
[4-(2-hydroxy-2-methylpropyl)phenyl]acetic acid

Guidance literature:: 2-(4-(2-ethoxy-2-oxoethyl)phenyl)acetic acid; methylmagnesium chloride; In tetrahydrofuran; at 0 - 20 ℃; for 18h;

With hydrogenchloride; water;