methyl 3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)propanoate

Base Information

Chemical Name:methyl 3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)propanoate
CAS No.:39739-01-0
Molecular Formula:C12H11 N O4
Molecular Weight:233.224
Hs Code.:
NSC Number:192712
DSSTox Substance ID:DTXSID10307552
Nikkaji Number:J427.004E
Wikidata:Q82054983

Synonyms:39739-01-0;methyl 3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)propanoate;methyl 3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate;methyl 3-(1,3-dioxoisoindolin-2-yl)propanoate;methyl 3-(1,3-dioxoisoindol-2-yl)propanoate;NSC192712;SCHEMBL12235840;DTXSID10307552;MFCD00600649;STK213083;AKOS002248659;NSC-192712;CS-0262657;EN300-83362;VU0608215-1;D84521;Z14667065;F3267-0046;methyl3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)propanoate

Suppliers and Price of methyl 3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of methyl 3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)propanoate

Chemical Property:

Vapor Pressure:1.36E-05mmHg at 25°C
Boiling Point:367.5°Cat760mmHg
Flash Point:176.1°C
Density:1.32g/cm³
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:233.06880783
Heavy Atom Count:17
Complexity:328

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CCN1C(=O)C2=CC=CC=C2C1=O

Technology Process of methyl 3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)propanoate

There total 10 articles about methyl 3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 136918-14-4,85-41-6
phthalimide

: 292638-85-8,9003-21-8,96-33-3
acrylic acid methyl ester

: 39739-01-0
methyl 3-(1,3-dioxoisoindolin-2-yl)propanoate

Guidance literature:: With ethanol; N-benzyl-N,N,N-triethylammonium chloride; sodium; for 5h; Heating;

Reference yield: 94.0%

: 64-18-6
formic acid

: methyl 3-(2-iodobenzamido)propanoate

: 39739-01-0
methyl 3-(1,3-dioxoisoindolin-2-yl)propanoate

Guidance literature:: With iodine; palladium diacetate; triethylamine; triphenylphosphine; In toluene; at 80 ℃; for 2h;
DOI:10.1016/j.tet.2019.01.023

Reference yield: 94.0%

: 67-56-1
methanol

: 3485-84-5,26809-43-8
N-vinylphthalimide

: 201230-82-2
carbon monoxide

: 39739-01-0
methyl 3-(1,3-dioxoisoindolin-2-yl)propanoate

Guidance literature:: With 1,3-bis(tert-butyl(pyridin-2-yl)phosphanyl)propane; palladium(II) acetylacetonate; toluene-4-sulfonic acid; for 20h; Sealed tube; Inert atmosphere; Autoclave;
DOI:10.1039/C8CC07470D