(S)-4-(4-bromo-2-chlorophenyl)-2-t-butoxycarbonylamino-2-methylbutan-1-ol

Base Information

Chemical Name:(S)-4-(4-bromo-2-chlorophenyl)-2-t-butoxycarbonylamino-2-methylbutan-1-ol
CAS No.:1260511-62-3
Molecular Formula:C₁₆H₂₃BrClNO₃
Molecular Weight:392.721
Hs Code.:

Synonyms:(S)-4-(4-bromo-2-chlorophenyl)-2-t-butoxycarbonylamino-2-methylbutan-1-ol

Suppliers and Price of (S)-4-(4-bromo-2-chlorophenyl)-2-t-butoxycarbonylamino-2-methylbutan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-4-(4-bromo-2-chlorophenyl)-2-t-butoxycarbonylamino-2-methylbutan-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-4-(4-bromo-2-chlorophenyl)-2-t-butoxycarbonylamino-2-methylbutan-1-ol

There total 3 articles about (S)-4-(4-bromo-2-chlorophenyl)-2-t-butoxycarbonylamino-2-methylbutan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1260511-60-1
methyl (S)-4-(4-bromo-2-chlorophenyl)-2-t-butoxycarbonylamino-2-methyl butyrate

: 1260511-62-3
(S)-4-(4-bromo-2-chlorophenyl)-2-t-butoxycarbonylamino-2-methylbutan-1-ol

Guidance literature:: With lithium borohydride; ethanol; In tetrahydrofuran; for 2h; Cooling with ice;

Reference yield:

: 916516-91-1
4-bromo-2-chloro-1-(2-iodoethyl)benzene

: 1260511-62-3
(S)-4-(4-bromo-2-chlorophenyl)-2-t-butoxycarbonylamino-2-methylbutan-1-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: n-butyllithium / hexane; tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

1.2: 1.5 h / -78 - 0 °C

2.1: hydrogenchloride / 1,4-dioxane / 1 h / 20 °C

2.2: 1 h / 20 °C

3.1: lithium borohydride; ethanol / tetrahydrofuran / 2 h / Cooling with ice

With hydrogenchloride; lithium borohydride; n-butyllithium; ethanol; In tetrahydrofuran; 1,4-dioxane; hexane;

Reference yield:

: 1260511-58-7
(2S,5R)-2-(4-bromo-2-chlorophenyl)ethyl-3,6-dimethoxy-2-methyl-5-isopropyl-2,5-dihydropyrazine

: 1260511-62-3
(S)-4-(4-bromo-2-chlorophenyl)-2-t-butoxycarbonylamino-2-methylbutan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride / 1,4-dioxane / 1 h / 20 °C

1.2: 1 h / 20 °C

2.1: lithium borohydride; ethanol / tetrahydrofuran / 2 h / Cooling with ice

With hydrogenchloride; lithium borohydride; ethanol; In tetrahydrofuran; 1,4-dioxane;