(4R,5R)-cis-4--5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan

Base Information

Chemical Name:(4R,5R)-cis-4--5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan
CAS No.:130718-74-0
Molecular Formula:C₂₇H₃₀O₃S₂
Molecular Weight:466.665
Hs Code.:

(4R,5R)-cis-4-<bis(p-tolylthio)methyl>-5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan

Synonyms:(4R,5R)-cis-4--5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan

Suppliers and Price of (4R,5R)-cis-4--5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4R,5R)-cis-4--5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4R,5R)-cis-4--5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan

There total 10 articles about (4R,5R)-cis-4--5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 130718-70-6,130718-72-8,130796-24-6
erythro 3-(4-methoxyphenyl)-1,1-bis(p-tolylthio)propane-2,3-diol

: 77-76-9
2,2-dimethoxy-propane

: 130718-74-0,130796-26-8,130796-28-0
cis-4--5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan

Guidance literature:: With para-toluene-4-sulphonic acid; Ambient temperature;

Reference yield:

: 32174-38-2
methyl (R)-2-hydroxy-2-(4-methoxyphenyl)acetate

: 130718-74-0
(4R,5R)-cis-4--5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan

Guidance literature:: Multi-step reaction with 5 steps

1: 96 percent / imidazole, 4-(dimethylamino)pyridine / diethyl ether / Ambient temperature

2: 1.) BuLi / 1.) hexane, THF, 0 deg C, 1 h, 2.) -78 deg C, 1 h

3: 96 percent / 1 M hydrochloric acid / acetone / 2 h

4: 82 percent / NaBH₄ / ethanol / 0.67 h / Ambient temperature

5: 4-toluenesulfonic acid / Ambient temperature

With 1H-imidazole; hydrogenchloride; dmap; sodium tetrahydroborate; n-butyllithium; toluene-4-sulfonic acid; In diethyl ether; ethanol; acetone;

Reference yield:

: 130718-65-9
(R)-3-(4-methoxyphenyl)-1,1-bis(p-tolylthio)-3-(trimethylsilyloxy)propan-2-one

: 130718-74-0
(4R,5R)-cis-4--5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / 1 M hydrochloric acid / acetone / 2 h

2: 82 percent / NaBH₄ / ethanol / 0.67 h / Ambient temperature

3: 4-toluenesulfonic acid / Ambient temperature

With hydrogenchloride; sodium tetrahydroborate; toluene-4-sulfonic acid; In ethanol; acetone;