1,1-dimethyl-4-phenylpentanol

Base Information

• Chemical Name: 1,1-dimethyl-4-phenylpentanol
• CAS No.: 51193-79-4
• Molecular Formula: C₁₃H₂₀O
• Molecular Weight: 192.301
• Mol file: 51193-79-4.mol

Synonyms:1,1-dimethyl-4-phenylpentanol

Chemical Property of 1,1-dimethyl-4-phenylpentanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1-dimethyl-4-phenylpentanol

There total 9 articles about 1,1-dimethyl-4-phenylpentanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

dihydro-α-norcurcumenic acid methylester (20881-29-2) + methylmagnesium bromide (75-16-1) → 1,1-dimethyl-4-phenylpentanol (51193-79-4)

Guidance literature:

dihydro-α-norcurcumenic acid methylester; methylmagnesium bromide; In tetrahydrofuran; diethyl ether; at -78 - 60 ℃; for 3h; Inert atmosphere; Sealed tube;

With water; ammonium chloride;

DOI:10.1021/jacs.0c02126

Reference yield:

diethyl ether (60-29-7,927820-24-4) + 1-bromo-3-phenylbutane (5801-17-2) + acetone (67-64-1) → sec-Butylbenzene (135-98-8,36383-15-0) + 1,1-dimethyl-4-phenylpentanol (51193-79-4)

Guidance literature:

DOI:10.1177/107110070002101004

Reference yield:

4-phenyl-1-pentanoic acid (16433-43-5) → 1,1-dimethyl-4-phenylpentanol (51193-79-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / acetyl chloride

2: diethyl ether / Ambient temperature

With acetyl chloride; In diethyl ether;

DOI:10.1021/ja00350a042

upstream raw materials:

methyl magnesium iodide

dihydro-α-norcurcumenic acid methylester

diethyl ether

1-bromo-3-phenylbutane

Downstream raw materials:

3,3,6-Trimethyl-6-phenyl-[1,2]dioxane

1,1,4-trimethyl-tetralin