Methanesulfonic acid 5-Boc-amino-pentyl ester

Base Information

• Chemical Name: Methanesulfonic acid 5-Boc-amino-pentyl ester
• CAS No.: 142342-55-0
• Molecular Formula: C11H23 N O5 S
• Molecular Weight: 281.373
• Hs Code.: 2924199090
• DSSTox Substance ID: DTXSID70931413
• Wikidata: Q82906968
• Mol file: 142342-55-0.mol

Synonyms:142342-55-0;Methanesulfonic acid 5-Boc-amino-pentyl ester;MFCD08448236;5-[(2-methylpropan-2-yl)oxycarbonylamino]pentyl methanesulfonate;5-(tert-butoxycarbonylamino)pentyl methanesulfonate;tert-butyl N-[5-(methanesulfonyloxy)pentyl]carbamate;SCHEMBL1057873;DTXSID70931413;BMDRTAQNZSCQKT-UHFFFAOYSA-N;AKOS015996519;DB-042622;Methanesulfonic acid 5-tert-butoxycarbonylamino-pentyl ester;5-{[tert-Butoxy(hydroxy)methylidene]amino}pentyl methanesulfonate

Chemical Property of Methanesulfonic acid 5-Boc-amino-pentyl ester

Chemical Property:

• Vapor Pressure: 8.66E-08mmHg at 25°C
• Refractive Index: 1.464
• Boiling Point: 435.6°Cat760mmHg
• Flash Point: 217.2°C
• PSA: 90.08000
• Density: 1.126g/cm³
• LogP: 3.12930
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 9
• Exact Mass: 281.12969401
• Heavy Atom Count: 18
• Complexity: 339

Purity/Quality:

98%Min ^*data from raw suppliers

5-Boc-amino-pentylMethanesulfonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)OC(=O)NCCCCCOS(=O)(=O)C
• Uses: 5-Boc-amino-pentyl Methanesulfonate can be used to treat cancer.

Technology Process of Methanesulfonic acid 5-Boc-amino-pentyl ester

There total 9 articles about Methanesulfonic acid 5-Boc-amino-pentyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-(tert-butyloxycarbonyl)-5-aminopentanol (75178-90-4) + methanesulfonyl chloride (124-63-0) → diethyl {5-[(tert-butoxycarbonyl)amino]pentyl }-propanedioate (142342-55-0)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃;

Reference yield: 99.0%

6-(Boc-amino)-1-hexanol (75937-12-1) + methanesulfonyl chloride (124-63-0) → diethyl {5-[(tert-butoxycarbonyl)amino]pentyl }-propanedioate (142342-55-0)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 0.5h; Inert atmosphere;

Reference yield:

N-(tert-butyloxycarbonyl)-5-aminopentanol (75178-90-4) → diethyl {5-[(tert-butoxycarbonyl)amino]pentyl }-propanedioate (142342-55-0)

Guidance literature:

With methanesulfonyl chloride; triethylamine; In DCM; at 20 ℃; for 1h;

upstream raw materials:

N-(tert-butyloxycarbonyl)-5-aminopentanol

methanesulfonyl chloride

5-hydroxypentylamine

di-tert-butyl dicarbonate

Downstream raw materials:

[5-(benzyl-methyl-amino)-pentyl]-carbamic acid tert-butyl ester

N¹-benzyl-N¹-methylpentane-1,5-diamine

NPTX-11

((S)-4-tert-Butoxycarbonylamino-4-{5-[(S)-3-carbamoyl-2-(2-1H-indol-3-yl-acetylamino)-propionylamino]-pentylcarbamoyl}-butyl)-carbamic acid benzyl ester