(S)-Tetrahydrofuran-2-carbonitrile

Base Information Edit

Chemical Name:(S)-Tetrahydrofuran-2-carbonitrile
CAS No.:539820-24-1
Molecular Formula:C5H7NO
Molecular Weight:97.12
Hs Code.:
European Community (EC) Number:634-877-1
Mol file:539820-24-1.mol

Synonyms:(S)-Tetrahydrofuran-2-carbonitrile;(2S)-oxolane-2-carbonitrile;539820-24-1;AKOS006294394

Suppliers and Price of (S)-Tetrahydrofuran-2-carbonitrile

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (S)-Tetrahydrofuran-2-carbonitrile Edit

Chemical Property:

PSA：33.02000
LogP:0.68898
XLogP3:0.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:97.052763847
Heavy Atom Count:7
Complexity:102

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:F,Xn
Statements: 11-20/21/22-36/37/38-43-37-36-22
Safety Statements: 16-26-36-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(OC1)C#N
Isomeric SMILES:C1C[C@H](OC1)C#N

Technology Process of (S)-Tetrahydrofuran-2-carbonitrile

There total 2 articles about (S)-Tetrahydrofuran-2-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 38694-47-2
4-bromobutyraldehyde

: 631-57-2
Acetyl cyanide

: 539820-24-1
(S)-tetrahydrofuran-2-carbonitrile

: 1393708-93-4
(R)-4-bromo-1-cyanobutyl acetate

: 164472-78-0
(R)-(tetrahydrofuran-2-yl)carbonitrile

: (S)-4-bromo-1-cyanobutyl alcohol

Guidance literature:: With Candida antarctica lipase B; di-μ-oxo-di((S,S)-N,N'-bis((salicylaldehydo)ethylenediamine))dititanium(IV); water; In toluene; at 20 ℃; for 15h; pH=6; optical yield given as %ee; enantioselective reaction; aq. buffer; Enzymatic reaction;
DOI:10.1016/j.tet.2012.05.090