METHYL 3-CYANO-4-ISOPROPOXYBENZOATE

Base Information

• Chemical Name: METHYL 3-CYANO-4-ISOPROPOXYBENZOATE
• CAS No.: 213598-11-9
• Molecular Formula: C12H13NO3
• Molecular Weight: 219.24
• Hs Code.: 2926909090
• Mol file: 213598-11-9.mol

Synonyms:METHYL 3-CYANO-4-ISOPROPOXYBENZOATE;Methyl 3-cyano-4-[(1-Methylethyl)oxy]benzoate

Chemical Property of METHYL 3-CYANO-4-ISOPROPOXYBENZOATE

Chemical Property:

• Boiling Point: 356.6±27.0 °C(Predicted)
• PSA: 59.32000
• Density: 1.14±0.1 g/cm3(Predicted)
• LogP: 2.13208
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

Methyl3-cyano-4-isopropoxybenzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL 3-CYANO-4-ISOPROPOXYBENZOATE

There total 15 articles about METHYL 3-CYANO-4-ISOPROPOXYBENZOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-iodo-propane (75-30-9) + methyl 3-cyano-4-hydroxybenzoate (156001-68-2) → methyl 3-cyano-4-[(1-methylethyl)oxy]benzoate (213598-11-9)

Guidance literature:

With potassium carbonate; In DMF (N,N-dimethyl-formamide); at 50 ℃; for 16h;

Reference yield: 100.0%

3-cyano-4-isopropoxybenzoic acid (258273-31-3) + methanol (67-56-1) → methyl 3-cyano-4-[(1-methylethyl)oxy]benzoate (213598-11-9)

Guidance literature:

3-cyano-4-isopropoxybenzoic acid; methanol; With diazomethyl-trimethyl-silane; In dichloromethane; at 0 - 20 ℃; for 1.8h;

With acetic acid; In dichloromethane; at 20 ℃;

Reference yield: 99.0%

isopropyl bromide (75-26-3) → methyl 3-cyano-4-[(1-methylethyl)oxy]benzoate (213598-11-9)

Guidance literature:

With potassium carbonate; In DMF (N,N-dimethyl-formamide); at 90 ℃;

upstream raw materials:

methyl 3-bromo-4-isopropoxybenzoate

dicyanozinc

isopropyl bromide

2-iodo-propane

Downstream raw materials:

3-cyano-4-isopropoxybenzoic acid

1,1-dimethylethyl 6-(5-{3-cyano-4-[(1-methylethyl)oxy] phenyl}-1,2,4-oxadiazol-3-yl)-1,2,4,5-tetrahydro-3H-3-benzazepine-3-carboxylate

1-((3-(3-cyano-4-isopropoxyphenyl)-4,5-dihydronaphtho-[1,2-c]isoxazol-7-yl)methyl)azetidine-3-carboxylic acid

3-(3-(3-cyano-4-isopropoxyphenyl)-4,5-dihydronaphtho[1,2-c]isoxazol-7-yl)propanoic acid