methyl (2R)-3-[tert-butyl(dimethyl)silyl]oxy-2-methylpropanoate

Base Information

Chemical Name:methyl (2R)-3-[tert-butyl(dimethyl)silyl]oxy-2-methylpropanoate
CAS No.:105859-44-7
Molecular Formula:C11H24O3Si
Molecular Weight:232.39200
Hs Code.:
DSSTox Substance ID:DTXSID40474140
Nikkaji Number:J1.065.665F
Mol file:105859-44-7.mol

Synonyms:105859-44-7;methyl (2R)-3-[tert-butyl(dimethyl)silyl]oxy-2-methylpropanoate;(2R)-METHYL 3-{[TERT-BUTYLDIMETHYLSILYL)OXY]}-2-METHYLPROPIONATE;GDTYFCRFIVSEIF-SECBINFHSA-N;SCHEMBL1751319;DTXSID40474140;EN300-9481871;methyl (r)-3-t-butyldimethylsilyloxy-2-methylpropanoate;methyl (R)-3-((tert-butyldimethylsilyl)oxy)-2-methylpropanoate;(R)-3-(tert-Butyldimethylsilyloxy)-2-methylpropionic acid methyl ester;METHYL (2R)-3-[(TERT-BUTYLDIMETHYLSILYL)OXY]-2-METHYLPROPANOATE

Suppliers and Price of methyl (2R)-3-[tert-butyl(dimethyl)silyl]oxy-2-methylpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2R)-Methyl3-{[tert-Butyldimethylsilyl)oxy]}-2-methylpropionate
500mg
$ 215.00

Medical Isotopes, Inc.
(2R)-Methyl3-[[tert-Butyldimethylsilyl)oxy]]-2-methylpropionate
5 g
$ 1720.00

Medical Isotopes, Inc.
(2R)-Methyl3-[[tert-Butyldimethylsilyl)oxy]]-2-methylpropionate
1 g
$ 840.00

American Custom Chemicals Corporation
(2R)-METHYL-3-([TERT-BUTYLDIMETHYLSILYL)OXY])-2-METHYLPROPIONATE 95.00%
5MG
$ 502.27

Total 7 raw suppliers

Chemical Property of methyl (2R)-3-[tert-butyl(dimethyl)silyl]oxy-2-methylpropanoate

Chemical Property:

PSA：35.53000
LogP:2.81730
Storage Temp.:Refrigerator
Solubility.:Dichloromethane, Ether, Ethyl Acetate, Hexane
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:232.14947116
Heavy Atom Count:15
Complexity:218

Purity/Quality:

99% ^*data from raw suppliers

(2R)-Methyl3-{[tert-Butyldimethylsilyl)oxy]}-2-methylpropionate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CO[Si](C)(C)C(C)(C)C)C(=O)OC
Isomeric SMILES:C[C@H](CO[Si](C)(C)C(C)(C)C)C(=O)OC
Uses (2R)-Methyl 3-{[tert-Butyldimethylsilyl)oxy]}-2-methylpropionate (cas# 105859-44-7) is a compound useful in organic synthesis.

Technology Process of methyl (2R)-3-[tert-butyl(dimethyl)silyl]oxy-2-methylpropanoate

There total 4 articles about methyl (2R)-3-[tert-butyl(dimethyl)silyl]oxy-2-methylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 72657-23-9,42998-03-8
methyl (R)-3-hydroxy-2-methylpropionate

: 18162-48-6
tert-butyldimethylsilyl chloride

: 105859-44-7
methyl (R)-2-methyl-3-[(tert-butyldimethylsilyl)oxy]propionate

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 5 ℃;
DOI:10.1007/BF02033860

Reference yield:

: 67-56-1
methanol

: 104701-87-3
(2S)-3-(tert-butyl-dimethyl-silyloxy)-2-methyl-propanal

: 105859-44-7
methyl (R)-2-methyl-3-[(tert-butyldimethylsilyl)oxy]propionate

: 93454-85-4
(S)-3-(tert-butyldimethylsilyloxy)-2-methylpropionic acid methyl ester

Guidance literature:: With 3,5,3',5'-tetra-tert-butyl-4,4'-diphenoquinone; C₂₃H₁₉Cl₃N₃⁽¹⁺⁾*Cl^(1-); benzoic acid; In tetrahydrofuran; at 20 ℃; for 4h; Overall yield = 95 percent;
DOI:10.1002/anie.202104712

Reference yield:

: 144828-45-5
2-(tert-butyl-dimethyl-silanyloxymethyl)-acrylic acid methyl ester

: 105859-44-7
methyl (R)-2-methyl-3-[(tert-butyldimethylsilyl)oxy]propionate

Guidance literature:: With D-glucose; NAD+; In water; at 30 ℃; for 24h; optical yield given as %ee; aq. buffer; Enzymatic reaction;
DOI:10.1002/adsc.201000522