(1S,2S)-Diethyl cyclopropane-1,2-dicarboxylate

Base Information

Chemical Name:(1S,2S)-Diethyl cyclopropane-1,2-dicarboxylate
CAS No.:889461-57-8
Molecular Formula:C₉H₁₄O₄
Molecular Weight:186.208
Hs Code.:
Mol file:889461-57-8.mol

Synonyms:

Suppliers and Price of (1S,2S)-Diethyl cyclopropane-1,2-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(1S,?2S)?-1,?2-?Cyclopropanedicarbox?ylicAcid1,?2-?DiethylEster
1g
$ 340.00

TRC
(1S,?2S)?-1,?2-?Cyclopropanedicarbox?ylicAcid1,?2-?DiethylEster
5g
$ 1670.00

Crysdot
(1S,2S)-Diethylcyclopropane-1,2-dicarboxylate 95+%
1g
$ 1042.00

Total 6 raw suppliers

Chemical Property of (1S,2S)-Diethyl cyclopropane-1,2-dicarboxylate

Chemical Property:

Storage Temp.:-20°C Freezer
Solubility.:Dichloromethane; Ethyl Acetate; Methanol

Purity/Quality:

99%, ^*data from raw suppliers

(1S,?2S)?-1,?2-?Cyclopropanedicarbox?ylicAcid1,?2-?DiethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses (1S,?2S)?-1,?2-?Cyclopropanedicarbox?ylic Acid 1,?2-?Diethyl Ester is an intermediate in synthesizing (O846925), (2S,3S)-2,3-Oxiranedicarboxylic Acid Monoethyl Ester is used in the synthesis of aza-peptidyl inhibitors of lysosomal asparaginyl endopeptidase, legumain. Also used in the synthesis of irreversible epidermal growth factor receptor inhibitors and probes for cathespins.

Technology Process of (1S,2S)-Diethyl cyclopropane-1,2-dicarboxylate

There total 4 articles about (1S,2S)-Diethyl cyclopropane-1,2-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 3999-55-1
diethyl trans-cyclopropane-1,2-dicarboxylate

: 613261-14-6
(-)-(R,R)-cyclopropane-1,2-dicarboxylic acid ethyl ester

: 889461-57-8
(+)-(S,S)-cyclopropane-1,2-dicarboxylic acid diethyl ester

Guidance literature:: With water; sodium hydroxide; at 28 ℃; pH=7; aq. phosphate buffer; Enzymatic reaction;
DOI:10.1039/b812777h

Reference yield: 45.0%

: 623-73-4
diazoacetic acid ethyl ester

: 140-88-5,9003-32-1
ethyl acrylate

: 889461-57-8
(+)-(S,S)-cyclopropane-1,2-dicarboxylic acid diethyl ester

: 889461-58-9
diethyl (-)-(1R,2R)-1,2-cyclopropanedicarboxylate

Guidance literature:: With (1,5-cyclooctadiene)(pyridine)(tricyclohexylphosphine)iridium (I) hexafluorophosphate; In dichloromethane; at 20 ℃; for 12h; stereoselective reaction; Inert atmosphere;
DOI:10.1002/anie.201300468