Benzyl[(4-methoxyphenyl)methyl]amine

Base Information

• Chemical Name: Benzyl[(4-methoxyphenyl)methyl]amine
• CAS No.: 14429-02-8
• Molecular Formula: C15H17NO
• Molecular Weight: 227.306
• Hs Code.: 2922299090
• European Community (EC) Number: 877-783-8
• DSSTox Substance ID: DTXSID90353355
• Nikkaji Number: J896.529C
• Wikidata: Q82130898
• Mol file: 14429-02-8.mol

Synonyms:14429-02-8;benzyl[(4-methoxyphenyl)methyl]amine;N-benzyl-1-(4-methoxyphenyl)methanamine;Benzyl-(4-methoxybenzyl)amine;Benzyl-(4-methoxy-benzyl)-amine;n-benzyl-4-methoxybenzylamine;N-[(4-methoxyphenyl)methyl]-1-phenylmethanamine;Benzenemethanamine, 4-methoxy-N-(phenylmethyl)-;CBMicro_025161;CBMicro_047998;Oprea1_083007;Oprea1_365043;benzyl (4-methoxybenzyl)amine;SCHEMBL1279045;DTXSID90353355;WZUBICZIDUTTNJ-UHFFFAOYSA-N;HMS1611J19;n-benzyl-n-(4-methoxybenzyl)amine;AMY30545;CCG-12064;MFCD01002920;STK196079;AKOS000227352;SB80074;BIM-0025008.P001;N-BENZYL(4-METHOXYPHENYL)METHANAMINE;CS-0216049;EU-0041317;EN300-32609;VU0093214-2;F79842;Z86130121

Chemical Property of Benzyl[(4-methoxyphenyl)methyl]amine

Chemical Property:

• Melting Point: 56 °C(Solv: methanol (67-56-1))
• Boiling Point: 170-172 °C(Press: 3 Torr)
• PKA: 9.15±0.20(Predicted)
• PSA: 21.26000
• Density: 1.053±0.06 g/cm3(Predicted)
• LogP: 3.37590
• Storage Temp.: 2-8°C
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 227.131014166
• Heavy Atom Count: 17
• Complexity: 193

Purity/Quality:

98%min ^*data from raw suppliers

Benzyl-(4-methoxy-benzyl)-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)CNCC2=CC=CC=C2

Technology Process of Benzyl[(4-methoxyphenyl)methyl]amine

There total 60 articles about Benzyl[(4-methoxyphenyl)methyl]amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-methoxy-benzaldehyde (123-11-5) + benzylamine (100-46-9) → benzyl-(4-methoxybenzyl)amine (14429-02-8)

Guidance literature:

With acetic acid; 1-hydrosilatrane; at 20 ℃; for 18h; Green chemistry;

DOI:10.1002/adsc.201700079

Reference yield: 97.0%

(E)-N-benzyl-1-(4-methoxyphenyl)methanimine (130517-94-1) → benzyl-(4-methoxybenzyl)amine (14429-02-8)

Guidance literature:

With Dimethylphenylsilane; tris(pentafluorophenyl)borate; In toluene; at 70 ℃; for 17.5h;

DOI:10.1021/ol006695q

Reference yield: 96.0%

benzaldehyde (100-52-7) + 4-methoxy-benzylamine (2393-23-9) → benzyl-(4-methoxybenzyl)amine (14429-02-8)

Guidance literature:

benzaldehyde; 4-methoxy-benzylamine; In methanol; at 20 ℃; for 3h; Inert atmosphere;

With magnetic borohydride exchange resin; In methanol; at 20 ℃; for 16h; Inert atmosphere;

DOI:10.1002/chem.201300358

upstream raw materials:

N-(4-methoxylbenzylidene)benzylamine

benzaldehyde

4-methoxy-benzylamine

N-Benzyl-N-(4-methoxy-benzyl)-4-nitro-benzenesulfonamide

Downstream raw materials:

benzyl-(4-methoxy-benzyl)-(2-piperidino-ethyl)-amine

benzyl-(4-methoxy-benzyl)-(2-morpholin-4-yl-ethyl)-amine

1-butyl-2-(ethoxycarbonyl)-N-benzyl-N-(p-methoxybenzyl)aziridine-2-carboxamide

(1R,2S)-2-Hydroxymethyl-cyclopropanecarboxylic acid benzyl-(4-methoxy-benzyl)-amide