[2-(Trimethylsiloxy)ethyl]benzene

Base Information

• Chemical Name: [2-(Trimethylsiloxy)ethyl]benzene
• CAS No.: 14629-58-4
• Molecular Formula: C11H18OSi
• Molecular Weight: 194.349
• Hs Code.: 2931900090
• Mol file: 14629-58-4.mol

Synonyms:PhCH2CH2OSiMe3;Ph-CH2CH2OTMS;2-phenylethyl TMS ether;1-trimethylsilyloxy-2-phenylethane;C6H5CH2CH2OTMS;

Chemical Property of [2-(Trimethylsiloxy)ethyl]benzene

Chemical Property:

• PSA: 9.23000
• LogP: 3.08060

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [2-(Trimethylsiloxy)ethyl]benzene

There total 21 articles about [2-(Trimethylsiloxy)ethyl]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-phenylethanol (60-12-8) + ethenyltrimethylsilane (754-05-2) → ethene (74-85-1) + trimethyl(phenethyloxy)silane (14629-58-4)

Guidance literature:

hydrogenchloride; chlorobis(ethylene)rhodium(I) dimer; In 1,4-dioxane; chloroform; at 20 ℃; for 2h; Product distribution / selectivity;

Reference yield: 99.0%

2-phenylethanol (60-12-8) + 1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) → trimethyl(phenethyloxy)silane (14629-58-4)

Guidance literature:

With SBA-15-supported cobalt(II) nanocatalyst; In neat (no solvent); at 20 ℃; for 0.25h;

DOI:10.1002/cbdv.201200071

Reference yield: 98.0%

1,1,1,2,2,2-hexamethyldisilane (1450-14-2) + 2-phenylethanol (60-12-8) → trimethyl(phenethyloxy)silane (14629-58-4)

Guidance literature:

With lanthanum(III) nitrate hexahydrate; In acetonitrile; at 20 ℃;

DOI:10.1080/10426500802509616

upstream raw materials:

chloro-trimethyl-silane

2-phenylethanol

methyl(4-phenylbut-1-en-1-yl)sulfane

(E)-(1-methoxyprop-1-enyloxy)trimethylsilane

Downstream raw materials:

acetic acid phenethyl ester

(2,2-dichloroethyl)benzene

2-(2-phenylethoxy)tetrahydro-2H-pyran

2-phenylethyl tosylate

Refernces

• 1、 Chatani, Naoto,Fujii, Satoru,Kido, Yoichi,Nakayama, Yasuhide,Kajikawa, Yasuteru,Tokuhisa, Hideo,Fukumoto, Yoshiya,Murai, Shinji. "Co2(CO)8-catalyzed reactions of acetals or lactones with hydrosilanes and carbon monoxide. A new access to the preparation of 1,2-diol derivatives through siloxymethylation". . p. 81 - 90. Retrieved 2021/02/05.
• 2、 Zeynizadeh, Behzad,Sorkhabi, Serve. "Fast and efficient method for Silylation of alcohols and phenols with HMDS in the presence of bis-thiourea complexes of cobalt, nickel, copper and zinc chlorides". . p. 127 - 135. Retrieved 2018/02/06.