Furan, 2-((phenylmethoxy)methyl)-

Base Information

• Chemical Name: Furan, 2-((phenylmethoxy)methyl)-
• CAS No.: 16361-14-1
• Molecular Formula: C12H12O2
• Molecular Weight: 188.226
• DSSTox Substance ID: DTXSID60936851
• Nikkaji Number: J980.590G
• Wikidata: Q82913060
• Mol file: 16361-14-1.mol

Synonyms:16361-14-1;2-((Benzyloxy)methyl)furan;Furan, 2-((phenylmethoxy)methyl)-;Furan, 2-[(phenylmethoxy)methyl]-;2-[(BENZYLOXY)METHYL]FURAN;2-(Benzyloxymethyl)furan;SCHEMBL916262;DTXSID60936851

Chemical Property of Furan, 2-((phenylmethoxy)methyl)-

Chemical Property:

• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 188.083729621
• Heavy Atom Count: 14
• Complexity: 152

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COCC2=CC=CO2

Technology Process of Furan, 2-((phenylmethoxy)methyl)-

There total 20 articles about Furan, 2-((phenylmethoxy)methyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(2-furyl)methyl alcohol (98-00-0,25212-86-6,93793-62-5) + benzyl chloride (100-44-7) → 2-benzyloxymethylfuran (16361-14-1)

Guidance literature:

With sodium hydroxide; In dimethyl sulfoxide; for 5.75h;

DOI:10.1016/0040-4020(82)85036-9

Reference yield: 96.0%

(2-furyl)methyl alcohol (98-00-0,25212-86-6,93793-62-5) + benzyl bromide (100-39-0) → 2-benzyloxymethylfuran (16361-14-1)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; sodium hydride; In tetrahydrofuran; at 0 ℃; for 24h;

DOI:10.1016/S0040-4020(98)00547-X

Reference yield: 84.0%

titanium(IV)isopropoxide (546-68-9) + phenyl 5-O-benzyl-1,2,3-trideoxy-3-fluoro-1-seleno-β-D-erythro-pentofuranoside (220718-09-2) → 2-benzyloxymethylfuran (16361-14-1) + (2S,5R)-2-Benzyloxymethyl-5-isopropoxy-2,5-dihydro-furan

Guidance literature:

With tert.-butylhydroperoxide; triethylamine; In dichloromethane; toluene; at -15 - 20 ℃; for 28h;

DOI:10.1021/jo980911f

upstream raw materials:

2-Chloromethylfuran

benzyl alcohol

2-bromomethylfuran

(2-furyl)methyl alcohol

Downstream raw materials:

3-benzyloxymethyl-4-bromo-3,8-epoxy-7-oxo-6-oxabicyclo<3.2.1>octane-2-carboxylic acid

(1R,2R,3R,6R,7R,9S)-7-Benzyloxymethyl-2-bromo-5-oxo-4,8-dioxa-tricyclo[4.2.1.0^3,7]nonane-9-carboxylic acid

1-(5-Benzyloxymethyl-furan-2-yl)-2-(tert-butyl-dimethyl-silanyloxy)-ethanol

5-(Benzyloxymethyl)-2-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranozyl)furan