(S)-Benzyl 2-(hydroxymethyl)piperidine-1-carboxylate

Base Information

Chemical Name:(S)-Benzyl 2-(hydroxymethyl)piperidine-1-carboxylate
CAS No.:212557-00-1
Molecular Formula:C14H19NO3
Molecular Weight:249.31
Hs Code.:
DSSTox Substance ID:DTXSID40446908
Nikkaji Number:J971.679C
Wikidata:Q82265655
Mol file:212557-00-1.mol

Synonyms:(S)-Benzyl 2-(hydroxymethyl)piperidine-1-carboxylate;212557-00-1;BENZYL (2S)-2-(HYDROXYMETHYL)PIPERIDINE-1-CARBOXYLATE;phenylmethyl (2S)-2-(hydroxymethyl)-1-piperidinecarboxylate;SCHEMBL1190565;DTXSID40446908;UDGDHNGWPNSYCD-ZDUSSCGKSA-N;AB6214;(S)-1-Cbz-2-(hydroxymethyl)piperidine,97%;(S)-Benzyl2-(hydroxymethyl)piperidine-1-carboxylate;(2S)-2-(Hydroxymethyl)piperidine-1-carboxylic acid benzyl ester

Suppliers and Price of (S)-Benzyl 2-(hydroxymethyl)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-Benzyl2-(hydroxymethyl)piperidine-1-carboxylate 95+%
1g
$ 2657.00

AK Scientific
(S)-Benzyl2-(hydroxymethyl)piperidine-1-carboxylate
500mg
$ 3837.00

Total 5 raw suppliers

Chemical Property of (S)-Benzyl 2-(hydroxymethyl)piperidine-1-carboxylate

Chemical Property:

PSA：49.77000
LogP:2.10790
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:249.13649347
Heavy Atom Count:18
Complexity:264

Purity/Quality:

98%min ^*data from raw suppliers

(S)-Benzyl2-(hydroxymethyl)piperidine-1-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C(C1)CO)C(=O)OCC2=CC=CC=C2
Isomeric SMILES:C1CCN([C@@H](C1)CO)C(=O)OCC2=CC=CC=C2

Technology Process of (S)-Benzyl 2-(hydroxymethyl)piperidine-1-carboxylate

There total 18 articles about (S)-Benzyl 2-(hydroxymethyl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 41373-39-1
(S)-pipecolinol

: 1885-14-9
phenyl chloroformate

: 212557-00-1
(S)-2-hydroxymethyl-piperidine-1-carboxylic acid benzyl ester

Guidance literature:: With potassium carbonate; In toluene; acetonitrile; at 0 ℃; for 6h;
DOI:10.1016/j.tet.2013.10.082

Reference yield: 90.0%

: 41373-39-1
(S)-pipecolinol

: 501-53-1,94274-21-2
benzyl chloroformate

: 212557-00-1
(S)-2-hydroxymethyl-piperidine-1-carboxylic acid benzyl ester

Guidance literature:: With potassium carbonate; In acetonitrile; at 0 ℃; for 6h;
DOI:10.1016/j.tet.2013.05.055

Reference yield: 37.0%

: 123-20-6,24991-31-9
vinyl n-butyrate

: 105706-75-0
1-benzyloxycarbonyl-2-hydroxymethylpiperidine

: 212557-00-1
(S)-2-hydroxymethyl-piperidine-1-carboxylic acid benzyl ester

: 154499-13-5
benzyl (R)-2-(hydroxymethyl)piperidine-1-carboxylate

: (S)-2-Butyryloxymethyl-piperidine-1-carboxylic acid benzyl ester

Guidance literature:: vinyl n-butyrate; 1-benzyloxycarbonyl-2-hydroxymethylpiperidine; With acylase I from Aspergillus species; In toluene; at 20 ℃; for 6h; Enzymatic reaction;

With phosphate buffer; acylase I from Aspergillus species; In water; at 20 ℃; for 7h; pH=7.0; Enzymatic reaction;