METHYL 3-CHLORO-4-ISOPROPOXYBENZOATE

Base Information

• Chemical Name: METHYL 3-CHLORO-4-ISOPROPOXYBENZOATE
• CAS No.: 213598-06-2
• Molecular Formula: C11H13ClO3
• Molecular Weight: 228.675
• Mol file: 213598-06-2.mol

Synonyms:3-Chlor-4-hydroxyphenylcarbanilsaeure-isopropylester;4-Ohcipc;4-Hydroxychlorpropham;3-chloro-4-[(1-methylethyl)oxy]benzoic acid methyl ester;methyl 3-chloro-4-isopropyloxybenzoate;methyl 3-chloro-4-[(1-methylethyl)oxy]benzoate;Methyl 3-chloro-4-iso-propoxybenzoate;Carbamic acid,(3-chloro-4-hydroxyphenyl)-,1-methylethyl ester;3-chloro-4-isopropoxy-benzoic acid methyl ester;Isopropyl-3-chlor-4-hydroxycarbanilat;isopropyl N-(3-chloro-4-hydroxyphenyl) carbamate;3-Chlor-4-isopropoxy-benzoesaeure-methylester;

Chemical Property of METHYL 3-CHLORO-4-ISOPROPOXYBENZOATE

Chemical Property:

• Boiling Point: 312.8±22.0 °C(Predicted)
• PSA: 35.53000
• Density: 1.162±0.06 g/cm3(Predicted)
• LogP: 2.91380

Purity/Quality:

97% ^*data from raw suppliers

METHYL 3-CHLORO-4-ISOPROPOXYBENZOATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL 3-CHLORO-4-ISOPROPOXYBENZOATE

There total 9 articles about METHYL 3-CHLORO-4-ISOPROPOXYBENZOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

→ methyl 3-chloro-4-isopropoxybenzoate (213598-06-2)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 12h; Inert atmosphere;

Reference yield: 96.9%

methyl 4-hydroxy-3-chlorobenzoate (3964-57-6) + isopropyl bromide (75-26-3) → methyl 3-chloro-4-isopropoxybenzoate (213598-06-2)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 4h;

Reference yield: 90.0%

2-iodo-propane (75-30-9) + methyl 4-hydroxy-3-chlorobenzoate (3964-57-6) → methyl 3-chloro-4-isopropoxybenzoate (213598-06-2)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 18h;

upstream raw materials:

2-iodo-propane

methyl 4-hydroxy-3-chlorobenzoate

isopropyl bromide

ethanol

Downstream raw materials:

3-chloro-4-isopropoxy-benzoic acid

5-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-indazole

1-[5-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1-isoquinolinyl]-4-piperidinecarboxylic acid lithium salt

3-[5-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1-isoquinolinyl]propanoic acid lithium salt