Ethoxymethoxymethane

Base Information

• Chemical Name: Ethoxymethoxymethane
• CAS No.: 22251-34-9
• Molecular Formula: C4H10O2
• Molecular Weight: 90.1222
• European Community (EC) Number: 606-967-0
• DSSTox Substance ID: DTXSID60335380
• Nikkaji Number: J2.174.404B
• Wikidata: Q82101740
• Mol file: 22251-34-9.mol

Synonyms:ethoxymethoxymethane

Chemical Property of Ethoxymethoxymethane

Chemical Property:

• Vapor Pressure: 140mmHg at 25°C
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 90.068079557
• Heavy Atom Count: 6
• Complexity: 21.5

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOCOC

Technology Process of Ethoxymethoxymethane

There total 12 articles about Ethoxymethoxymethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

Dimethoxymethane (109-87-5) + formaldehyde diethyl acetal (462-95-3) → formaldehyde ethyl methyl acetal (22251-34-9)

Guidance literature:

With boron trifluoride diethyl etherate; at 35 ℃; for 5h;

Reference yield: 10.0%

diethyl acetal (105-57-7,30846-29-8) + Dimethoxymethane (109-87-5) → 1,1-dimethoxyethane (534-15-6) + formaldehyde ethyl methyl acetal (22251-34-9) + formaldehyde diethyl acetal (462-95-3) + acetaldehyde ethyl methyl acetal (10471-14-4)

Guidance literature:

With KU-2 resin; at 40 ℃; for 5h;

Reference yield:

Dimethoxymethane (109-87-5) + ethanol (64-17-5) → formaldehyde ethyl methyl acetal (22251-34-9) + formaldehyde diethyl acetal (462-95-3)

Guidance literature:

With NKC-9; at 70 ℃; for 4h; under 7500.75 - 15001.5 Torr; Reagent/catalyst; Concentration; Temperature; Pressure; Autoclave; Inert atmosphere;

upstream raw materials:

methanol

formaldehyd

ethanol

chloromethyl methyl ether

Downstream raw materials:

(2RS,5RS,9SR,10RS)-9-methoxymethoxy-6,10-dimethyl-2-pivaloyloxyspiro<4.5>dec-6-en-8-one

(2RS,5RS,8SR,9SR,10RS)-8,9-bis(methoxymethoxy)-6,10-dimethyl-2-pivaloyloxyspiro<4.5>dec-6-ene

Refernces

• 1、 Belkina, E. G.,Gruzdev, M. S.,Kalmykov, P. A.,Klyuev, M. V.,Lysenok, A. A.,Magdalinova, N. A.. "Tetrachloromethane Hydrodechlorination over Palladium-Containing Nanodiamonds". . p. 1148 - 1153. Retrieved 2020/10/14.
• 2、 -. "Method for preparing ethoxymethoxy methane by using supported heteropoly acid". Paragraph 0022. . Retrieved 2017/06/24.