2-(2-methoxyphenyl)-1H-isoindole-1,3(2H)-dione

Base Information

Chemical Name:2-(2-methoxyphenyl)-1H-isoindole-1,3(2H)-dione
CAS No.:2314-77-4
Molecular Formula:C15H11NO3
Molecular Weight:253.257
Hs Code.:
DSSTox Substance ID:DTXSID001246938
Nikkaji Number:J871.387A
ChEMBL ID:CHEMBL319823
Mol file:2314-77-4.mol

Synonyms:2-(2-methoxyphenyl)-1H-isoindole-1,3(2H)-dione;n-(2-methoxyphenyl)phthalimide;2314-77-4;1H-Isoindole-1,3(2H)-dione, 2-(2-methoxyphenyl)-;2-(2-Methoxy-phenyl)-isoindole-1,3-dione;Oprea1_069912;Oprea1_408833;CBDivE_001917;CHEMBL319823;DTXSID001246938;CCG-15231;STK386360;AKOS000735419;NCGC00187708-01;EU-0033730;SR-01000391565;SR-01000391565-1

Suppliers and Price of 2-(2-methoxyphenyl)-1H-isoindole-1,3(2H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-(2-methoxyphenyl)-1H-isoindole-1,3(2H)-dione

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:253.07389321
Heavy Atom Count:19
Complexity:358

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=CC=C1N2C(=O)C3=CC=CC=C3C2=O

Technology Process of 2-(2-methoxyphenyl)-1H-isoindole-1,3(2H)-dione

There total 28 articles about 2-(2-methoxyphenyl)-1H-isoindole-1,3(2H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 6307-13-7
2-(2-hydroxyphenyl) isoindoline-1,3-dione

: 74-88-4
methyl iodide

: 2314-77-4
N-(2-methoxyphenyl)phthalimide

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1021/acs.joc.8b02899

Reference yield: 94.0%

: 64-18-6
formic acid

: 36684-47-6
2-iodo-N-(2-methoxy-phenyl)-benzamide

: 2314-77-4
N-(2-methoxyphenyl)phthalimide

Guidance literature:: With iodine; palladium diacetate; triethylamine; triphenylphosphine; In toluene; at 80 ℃; for 2h;
DOI:10.1016/j.tet.2019.01.023

Reference yield: 94.0%

: 615-42-9
1,2-Diiodobenzene

: 201230-82-2
carbon monoxide

: 90-04-0
2-methoxy-phenylamine

: 2314-77-4
N-(2-methoxyphenyl)phthalimide

Guidance literature:: With 1,4-diaza-bicyclo[2.2.2]octane; palladium 10% on activated carbon; In toluene; at 120 ℃; for 2h; under 4654.46 Torr; Autoclave;
DOI:10.1002/adsc.201100460