METHYL 2-(5-METHOXY-1H-INDOL-3-YL)-2-OXOACETATE

Base Information

• Chemical Name: METHYL 2-(5-METHOXY-1H-INDOL-3-YL)-2-OXOACETATE
• CAS No.: 99988-56-4
• Molecular Formula: C12H11NO4
• Molecular Weight: 233.224
• Hs Code.: 2918990090
• Mol file: 99988-56-4.mol

Synonyms:METHYL 2-(5-METHOXY-1H-INDOL-3-YL)-2-OXOACETATE;5-Methoxy-3-indoleglyoxylic acid Methyl ester;1H-INDOLE-3-ACETIC ACID, 5-METHOXY-α-OXO-, METHYL ESTER

Chemical Property of METHYL 2-(5-METHOXY-1H-INDOL-3-YL)-2-OXOACETATE

Chemical Property:

• PSA: 68.39000
• LogP: 1.53220

Purity/Quality:

97% ^*data from raw suppliers

1H-INDOLE-3-ACETICACID,5-METHOXY-α-OXO-,METHYLESTER 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL 2-(5-METHOXY-1H-INDOL-3-YL)-2-OXOACETATE

There total 9 articles about METHYL 2-(5-METHOXY-1H-INDOL-3-YL)-2-OXOACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methanol (67-56-1) + 5-methoxylindole (1006-94-6) + oxalyl dichloride (79-37-8) → methyl 2-(5-methoxy-1H-indol-3-yl)-2-oxoacetate (99988-56-4)

Guidance literature:

5-methoxylindole; oxalyl dichloride; In diethyl ether; at 0 ℃; for 1.5h;

methanol; In diethyl ether; at 0 ℃; for 1h;

Reference yield: 83.0%

5-methoxylindole (1006-94-6) + oxalyl dichloride (79-37-8) → methyl 2-(5-methoxy-1H-indol-3-yl)-2-oxoacetate (99988-56-4)

Guidance literature:

With sodium methylate; In methanol; diethyl ether; water; ethyl acetate;

Reference yield: 71.0%

5-methoxylindole (1006-94-6) + oxalyl dichloride (79-37-8) + sodium methylate (124-41-4) → methyl 2-(5-methoxy-1H-indol-3-yl)-2-oxoacetate (99988-56-4)

Guidance literature:

5-methoxylindole; oxalyl dichloride; In diethyl ether; at 0 - 5 ℃; for 1h;

sodium methylate; In methanol; diethyl ether; at -30 - -20 ℃; for 0.5h;

DOI:10.1002/ardp.201300008

upstream raw materials:

2-[5-(benzyloxy)-1H-indol-3-yl]-2-oxoacetyl chloride

(5-methoxy-1H-indol-3-yl)oxoacetyl chloride

sodium methylate

methanol

Downstream raw materials:

(5-methoxy-1H-indol-3-yl)acetic acid methyl ester

C₂₄H₂₈O₄N₂

5-methoxy-1H-indole-3-acetic acid

2-(1-benzyl-5-methoxy-1H-indol-3-yl)ethanol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 99988-56-4 METHYL 2-(5-METHOXY-1H-INDOL-3-YL)-2-OXOACETATE

Send

Send

Metric Ton KG G Pound L ML

Send

Send