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Sodium dimethylarsinate

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Name

Sodium dimethylarsinate

EINECS 204-708-2
CAS No. 124-65-2 Density N/A
PSA 40.13000 LogP 0.54920
Solubility N/A Melting Point 60oC
Formula C2H7AsO2.Na Boiling Point 253.1 °C at 760 mmHg
Molecular Weight 159.98 Flash Point 109.4 °C
Transport Information UN 1688 6.1/PG 2 Appearance white crystals or powder
Safety 20/21-28-45-60-61 Risk Codes 23/25-50/53
Molecular Structure Molecular Structure of 124-65-2 (Sodium cacodylate 97+) Hazard Symbols ToxicT; DangerousN
Synonyms

Arsineoxide, hydroxydimethyl-, sodium salt (8CI);Arsinic acid, dimethyl-, sodiumsalt (9CI);Sodium, [(dimethylarsino)oxy]-, As-oxide (7CI);Alkarsodyl;Arsecodile;Arsicodile;Arsycodile;Cacodylate sodium;Cacodylic acid sodiumsalt;Cacodylic acid sodium salt (1:1);Chemaid;Hydroxydimethylarsine oxidesodium salt;Sodium cacodylate;

 

Sodium dimethylarsinate Synthetic route

593-58-8

methylarsine oxide

74-88-4

methyl iodide

124-65-2

sodium cacodylate

Conditions
ConditionsYield
With methanol; sodium hydroxide
102829-02-7

diphenylantimony(V) bromide oxide

124-65-2

sodium cacodylate

196503-04-5

[(Sb(C6H5)2)2(O)2(O2As(CH3)2)2]

Conditions
ConditionsYield
In dichloromethane reflux (24 h); filtration, removal of solvent, crystn. (CHCl3/hexane); elem. anal.;86%

molybdic acid

7722-84-1

dihydrogen peroxide

124-65-2

sodium cacodylate

75-57-0

tetramethlyammonium chloride

N(CH3)4(1+)*(MoO(O2)2)2O2As(CH3)2(1-) = [N(CH3)4][(MoO(O2)2)2O2As(CH3)2]

Conditions
ConditionsYield
In ethanol; water stirring MoO3*H2O in aq. H2O2 at 30°C until a soln. was obtained,addn. of NaO2AsMe2 in EtOH at room temp. followed by addn. of (Me4N)Cl in H2O; addn. of EtOH, cooling to 4°C, filtration, washing (cold EtOH; Et2O), drying in air; elem. anal.;85%

thallium(III) acetate

124-65-2

sodium cacodylate

tris(dimethylarsinato)thallium

Conditions
ConditionsYield
In methanol at 20℃; for 3h; Darkness;82%
124-65-2

sodium cacodylate

1538-64-3

μ-oxo-bis[bromotriphenylantimony(V)]

196503-09-0

[(Sb(C6H5)3)2(O)(O2As(CH3)2)2]

Conditions
ConditionsYield
In dichloromethane reflux (20 h); filtration, removal of solvent (vac.), dissoln. (CHCl3), diffusion of hexane into the soln.; elem. anal.;74%

molybdic acid

1112-67-0

tetrabutyl-ammonium chloride

7722-84-1

dihydrogen peroxide

124-65-2

sodium cacodylate

N(C4H9)4(1+)*(MoO(O2)2)2O2As(CH3)2(1-) = [N(C4H9)4][(MoO(O2)2)2O2As(CH3)2]

Conditions
ConditionsYield
In ethanol; water stirring MoO3*H2O in aq. H2O2 at 30°C until a soln. was obtained,addn. of NaO2AsMe2 in EtOH at room temp. followed by addn. of (n-Bu4N)C l in H2O; addn. of EtOH, cooling to 4°C, filtration, washing (cold EtOH; Et2O), drying in air; elem. anal.;60%

zinc perchlorate

124-65-2

sodium cacodylate

452295-73-7

N,N-bis[2-(4,5-dimethyl)benzimidazolylmethyl]-N',N'-bis(2-pyridylmethyl)-1,3-diamino-2-propanol

[[Zn2(N,N-bis[(5,6-dimethyl)benzimidazolylmethyl]-N',N'-bis(2-pyridylmethyl)-1,3-diamino-2-propanolate](O2AsMe2)](ClO4)2*H2O

Conditions
ConditionsYield
In water; acetonitrile 2 equiv. of aq. Zn-salt soln. and 1 equiv. of aq. As-compd. soln. were added to MeCN soln. of N-base; crystn. by diffusion of Et2O into the soln. for 4 d, elem. anal.;55%
3375-31-3

palladium diacetate

124-65-2

sodium cacodylate

Pd16O24(OH)8(24-)*8C2H6As(3+)*1.25Na(1+)*0.25C2H3O2(1-)*C2H6AsO2(1-)*19H2O

Conditions
ConditionsYield
Stage #1: palladium diacetate; sodium cacodylate In aq. buffer at 20℃; for 48h; pH=7;
Stage #2: water
3%
124-65-2

sodium cacodylate

Dimethyldiselenoarsinsaeure

Conditions
ConditionsYield
With hydrogen selenide In ethanol
124-65-2

sodium cacodylate

sulfur dioxide

sulfur dioxide

503-80-0

bis-{dimethylarsenic}-oxide

Sodium dimethylarsinate Consensus Reports

Arsenic and its compounds are on the Community Right-To-Know List. EPA Extremely Hazardous Substances List. Reported in EPA TSCA Inventory.

Sodium dimethylarsinate Standards and Recommendations

OSHA PEL: TWA 0.5 mg(As)/m3
ACGIH TLV: BEI: 35 μ (As)/L inorganic arsenic and methylated metabolites in urine
DOT Classification:  6.1; Label: Poison

Sodium dimethylarsinate Specification

The CAS registry number of Hydroxydimethylarsine oxide, sodium salt is 124-65-2. Its EINECS registry number is 204-708-2. The IUPAC name is sodium dimethylarsinate. In addition, the molecular formula is C2H7AsO2.Na. What's more, it is an arsenical that has been used as a dermatologic agent and as an herbicide. And it should be stored in a cool and dry place.

Physical properties about Hydroxydimethylarsine oxide, sodium salt are: (1)ACD/LogP: -1.62; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -1.69; (4)ACD/LogD (pH 7.4): -2.76; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 2.69; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 37.3 Å2; (13)Flash Point: 109.4 °C; (14)Enthalpy of Vaporization: 56.98 kJ/mol; (15)Boiling Point: 253.1 °C at 760 mmHg; (16)Vapour Pressure: 0.00288 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
This chemical is toxic by inhalation and if swallowed. And it is very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. During using it, you can not eat, drink or smoke. If contact it with skin, wash it immediately with plenty of ... (to be specified by the manufacturer). In addition, in case of accident or if you feel unwell, seek medical advice immediately (show label where possible). What's more, this material and/or its container must be disposed of as hazardous waste. You should avoid release to the environment and you can refer to special instructions safety data sheet.

You can still convert the following datas into molecular structure:
(1)SMILES: [Na+].[O-][As](=O)(C)C
(2)InChI: InChI=1/C2H7AsO2.Na/c1-3(2,4)5;/h1-2H3,(H,4,5);/q;+1/p-1
(3)InChIKey: IHQKEDIOMGYHEB-REWHXWOFAN

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal > 1gm/kg (1000mg/kg)   National Technical Information Service. Vol. AD691-490,
mouse LD50 oral 4mg/kg (4mg/kg)   Compilation of LD50 Values of New Drugs.
rat LD50 oral 2600mg/kg (2600mg/kg)   Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 70, 1973.

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