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Basic Information
| CAS No.: | 78-00-2 |
|---|---|
| Name: | TETRAETHYLLEAD |
| Molecular Structure: | |
|
|
|
| Formula: | C8H20 Pb |
| Molecular Weight: | 323.447 |
| Synonyms: | Lead,tetraethyl-; NSC 22314; TEL; Tetraethyllead; Tetraethylplumbane |
| EINECS: | 201-075-4 |
| Density: | 1.653 g/mL at 25 ºC(lit.) |
| Melting Point: | -136.8 C |
| Boiling Point: | 84 - 85 C (Decomposes) |
| Flash Point: | 77 C |
| Solubility: | Insoluble Light yellow liquid |
| Hazard Symbols: |
|
| Risk Codes: | 61-26/27/28-33-50/53-62-38-10 |
| Transport Information: | 250kgs |
| PSA: | 0.00000 |
| LogP: | 3.51480 |
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- 78-00-2
tetraethyllead(IV)
Conditions
| Conditions | Yield |
|---|---|
| heated in vac. to 60°C for 8 h, under nitrogen, yellow-orange liquid became solid and darker orange in colour; dissolved in CH2Cl2/hexane solution, placed upon alumina column, elutedwith hexane, then hexane/CH2Cl2 solution, concentrated and placed refrigerator; | A 58% B n/a |
Conditions
| Conditions | Yield |
|---|---|
| Irradiation (UV/VIS); 12 h; | A 50% B n/a |
Conditions
| Conditions | Yield |
|---|---|
| With pyridine; lead sodium | |
| With pyridine; tetrasodium-monoplumbide; water at 38℃; | |
| With lead; sodium at 70℃; im geschlossenen Gefaess; |
Conditions
| Conditions | Yield |
|---|---|
| With lead sodium; water; toluene; potassium iodide |
Conditions
| Conditions | Yield |
|---|---|
| With lead sodium; hydrogen at 100℃; under 7355.08 Torr; |
Conditions
| Conditions | Yield |
|---|---|
| With lead; lead(II) iodide at 100 - 130℃; | |
| With lead sodium | |
| With hydrogenchloride; lead sodium |
Conditions
| Conditions | Yield |
|---|---|
| With lead(IV) chloride; Petroleum ether anfangs unter Kuehlung; |
Conditions
| Conditions | Yield |
|---|---|
| With PbS | |
| With lead(II) chloride | |
| With lead(II) oxide |
Conditions
| Conditions | Yield |
|---|---|
| Electrolysis.an einer Bleianode; |
Conditions
| Conditions | Yield |
|---|---|
| With lead(II) chloride | |
| With lead(II) chloride |
This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.
Chemistry
IUPAC Name: tetraethylplumbane
Molecular Formula:C8H20Pb
Molecular Weight:323.4444
Appearance:colorless, viscous liquid
Melting Point:136 °C(lit.)
Boiling Point:84-85 °C15 mm Hg(lit.)
density:1.653 g/mL at 25 °C(lit.)
refractive index:n20/D 1.519(lit.)
Fp:84 °F
Solubility:slightly soluble in ethanol;
soluble in benzene, petroleum ether, toluene, gasoline
Insolubility:Water
Synonyms of TETRAETHYL LEAD(78-00-2):TEL;TETRAETHYLLEAD;
(C2H5)4Pb;Czteroetylek olowiu;czteroetylekolowiu;czteroetylekolowiu(polish);Lead tetraethyl;lead,tetraethyl-
Categories of TETRAETHYL LEAD(78-00-2): Organometallics;Organolead;Organometallic Reagents;Others
Merck 13,9277
Uses
TETRAETHYL LEAD(78-00-2) is used as an antiknock agent.
Production
TETRAETHYL LEAD(78-00-2) is produced by reacting chloroethane with a sodium–lead alloy.
4 NaPb + 4 CH3CH2Cl → (CH3CH2)4Pb + 4 NaCl + 3 Pb
4 NaPb + 4 CH3CH2Cl → (CH3CH2)4Pb + 4 NaCl + 3 Pb
Toxicity Data With Reference
| 1. | otr-ham:emb 12,500 µg/L | AETODY Advances in Modern Environmental Toxicology. 1 (1980),241. | ||
| 2. | ihl-hmn TCLo:1749 g/m3/30M:NOSE,EYE,GIT | SAIGBL Sangyo Igaku. Japanese Journal of Industrial Health. 17 (1975),223. | ||
| 3. | unr-man LDLo:1470 µg/kg | 85DCAI Poisoning; Toxicology, Symptoms, Treatments. 2 (1970),73. | ||
| 4. | orl-rat LD50:12,300 µg/kg | EXPEAM Experientia. 28 (1972),923. | ||
| 5. | ihl-rat LC50:850 mg/m3/60M | BJIMAG British Journal of Industrial Medicine. 18 (1961),277. | ||
| 6. | ipr-rat LD50:15 mg/kg | MELAAD Medicina del Lavoro. Industrial Medicine. 54 (1963),486. | ||
| 7. | ivn-rat LD50:14,400 µg/kg | MELAAD Medicina del Lavoro. Industrial Medicine. 54 (1963),486. | ||
| 8. | par-rat LD50:15 mg/kg | AOHYA3 Annals of Occupational Hygiene. 3 (1961),226. | ||
| 9. | ihl-mus LCLo:650 mg/m3/7H | SAIGBL Sangyo Igaku. Japanese Journal of Industrial Health. 15 (1973),3. | ||
| 10. | skn-dog LDLo:547 mg/kg | SAIGBL Sangyo Igaku. Japanese Journal of Industrial Health. 15 (1973),3. |
Consensus Reports
IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 230.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 23 ,1980,p. 325.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 2 ,1973,p. 150.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Extremely Hazardous Substances List. Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.
Safety Profile
Safety Information of TETRAETHYL LEAD(78-00-2):
Human poison by an unspecified route. Experimental poison by ingestion, intraperitoneal, intravenous, subcutaneous, and parenteral routes. Moderately toxic by inhalation and skin contact. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental carcinogenic data. Mutation data reported. Lead compounds are particularly toxic to the central nervous system. It is a solvent for fatty materials and has some solvent action on rubber as well. The fact that it is a lipoid solvent makes it an industrial hazard because it can cause intoxication not only by inhalation but also by absorption through the skin. Decomposes when exposed to sunlight or allowed to evaporate; forms triethyl lead, which is also a poisonous compound, as one of its decomposition products. May cause elemental lead intoxication by coming in contact with the skin.
A combustible liquid when exposed to heat, flame, or oxidizers. Can react vigorously with oxidizing materials. Exposure to air for several days may cause explosive decomposition. To fight fire, use dry chemical, CO2, mist, foam. When heated to decomposition it emits toxic fumes of Pb. See also LEAD COMPOUNDS.
Hazard Codes T+,N
Risk Statements 61-26/27/28-33-50/53-62-38-10
Safety Statements 53-45-60-61-36/37-26
RIDADR UN 1649 6.1/PG 1
WGK Germany 3
RTECS TP4550000
TSCA Yes
HazardClass 6.1(a)
PackingGroup I
Human poison by an unspecified route. Experimental poison by ingestion, intraperitoneal, intravenous, subcutaneous, and parenteral routes. Moderately toxic by inhalation and skin contact. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental carcinogenic data. Mutation data reported. Lead compounds are particularly toxic to the central nervous system. It is a solvent for fatty materials and has some solvent action on rubber as well. The fact that it is a lipoid solvent makes it an industrial hazard because it can cause intoxication not only by inhalation but also by absorption through the skin. Decomposes when exposed to sunlight or allowed to evaporate; forms triethyl lead, which is also a poisonous compound, as one of its decomposition products. May cause elemental lead intoxication by coming in contact with the skin.
A combustible liquid when exposed to heat, flame, or oxidizers. Can react vigorously with oxidizing materials. Exposure to air for several days may cause explosive decomposition. To fight fire, use dry chemical, CO2, mist, foam. When heated to decomposition it emits toxic fumes of Pb. See also LEAD COMPOUNDS.
Hazard Codes T+,N
Risk Statements 61-26/27/28-33-50/53-62-38-10
Safety Statements 53-45-60-61-36/37-26
RIDADR UN 1649 6.1/PG 1
WGK Germany 3
RTECS TP4550000
TSCA Yes
HazardClass 6.1(a)
PackingGroup I
Standards and Recommendations
OSHA PEL: TWA 0.075 mg(Pb)/m3 (skin)
ACGIH TLV: TWA 0.1 mg(Pb)/m3 (skin); Not Classifiable as a Human Carcinogen
DFG MAK: 0.05 mg/m3
DOT Classification: 6.1; Label: Poison, Flammable Liquid
ACGIH TLV: TWA 0.1 mg(Pb)/m3 (skin); Not Classifiable as a Human Carcinogen
DFG MAK: 0.05 mg/m3
DOT Classification: 6.1; Label: Poison, Flammable Liquid
Analytical Methods
For occupational chemical analysis use NIOSH: Tetraethyl Lead (as Pb), 2533.