Ethynyl-cyclohexanol can be alkynylated with a suitable electrophile, often an aryl or vinyl halide, in the presence of a palladium catalyst. The reaction conditions typically include a base, such as triethylamine or sodium carbonate, which facilitates the deprotonation of ECH to generate the acetylide ion.
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2-((2-fluorophenyl)ethynyl)naphthalene
1-[2,4,6-trimethylphenylethynyl]-1,2-benziodoxol-3(1H)-one
Benzenemethanol, 2,3,4,5,6-pentafluoro-a-(phenylethynyl)-
(5-methylhex-1-yn-1-yl)diphenylphosphine oxide
(S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanoate
Benzene, 1-fluoro-4-(1-octynyl)-
1-(2,3-dimethoxyphenyl)-3-phenylprop-2-yn-1-ol
tert-butyl 4-(4-methoxyphenyl)-4-oxobut-2-yn-1-ylcarbamate
2-(naphthalen-2-yl)quinazolin-4(3Η)-one
